Vaccines The End of Illness

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Vaccines The End of Illness
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• Published April 2014
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Vaccines The End of Illness

• This report focuses on the most recent vaccine
  research, emphasizing their reputation as an
  unmatched tool of efficient healthcare. Their low
  cost, extended protection and the impossibility
  of their circumvention through development of
  resistance on the part of the target pathogen
  have been longstanding attributes of vaccines.
  Today, vaccine technology is undergoing a
  fundamental revolution, taking advantage of the
  profound understanding of the immune system and
  its ability to mount protective antibody
  production and cell-based responses to foreign
  antigens. Understanding these properties will not
  only enable the development of innovative
  diagnostics but also the advancement of
  therapeutic applications.
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Vaccines The End of Illness

• Specific Highlights Include
• This report profiles some of the major pharma
  companies involved in vaccine RD and a number of
  biotech companies developing new vaccine products
  and technologies - including 35 small pharma
  companies and 8 big pharma companies profiled
• The logistics and management of the vaccine
  industry are increasingly based on partnerships
  between the private sector (pharma and biotech
  companies), government agencies (WHO) and large
  non-profits (such as the Gates Foundation).
• An assessment of the future directions of
  vaccines as innovative medical therapies for a
  wide range of diseases.
• Explores conditions not normally thought to be in
  purview of vaccination, including substance abuse
  and neurological disorders such as Alzheimer's
  disease and Parkinson's disease.
• Survey of industry experts concerning the
  political economic and technological future of
  vaccine technology.

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Vaccines The End of Illness

• List of Figures
• Figure 1.1 Overall Decline in Worldwide Death
  RatesFigure 2.5 Application of Nano-Sized
  Delivery SystemsFigure 5.11 Emergent's ADAPTIR
  Design Technology for Antibody TherapeuticsFigure
  5.15 Genocea Technology for Screening Candidate
  Vaccines ComponentsFigure 6.2 Development of
  Anti-cancer Vaccine Products and the Regulatory
  Guidance Throughout the ProcessFigure 8.1
  Makeup of the Participants in the SurveyFigure
  8.2 Breakdown of Opinions of the Industrial
  Commitment of ResourcesFigure 8.3 How Should
  the Industry Focus its RD Efforts in Vaccine
  Technology?Figure 8.4 What are the Most
  Promising Cancer Vaccine Targets?Figure 8.5 How
  Seriously are the Federal Governmental Bodies
  Committed to Vaccine Technology?Figure 8.6
  State and Local Governmental Support for RD. How
  Does it Stack Up?Figure 8.7 The Softest Cancer
  Vaccine TargetFigure 8.8 Where is the Vaccine
  Market Headed?Figure 8.9 Why Would a Vaccine
  Development Program be Vetoed?Figure 8.10 The
  Fallout from Vaccine Denialism

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Vaccines The End of Illness

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• Figure 8.11 Where is Bioprocessing of Vaccines
  Headed?Figure 8.12 Cancer Vaccines Still a
  Long Ways OffFigure 8.13 AIDS Vaccines Further
  Down the Road than Cancer Vaccines?Figure 8.14
  The Road Ahead Daunting ChallengesFigure 8.15
  Is Regulatory Control of Vaccines a
  Problem?Figure 8.16 How Does the Industry Feel
  About Vaccines as a Barrier to Terroristic
  Threats?Figure 8.17 When Vaccines FailFigure
  8.18 Bioinformatics A Pathway to Innovative
  Vaccine AntigensFigure 8.19 Counteracting
  Vaccine DenialismFigure 8.20 Opinions on the
  Rise of Therapeutic VaccinesFigure 8.21 The
  Future of Oral VaccinesFigure 8.22 Vaccine
  Technology in the Third WorldFigure 8.23
  Vaccines and the Battle Against Hepatitis
  CFigure 8.24 Academic/Industrial Partnerships
  Do They Have a Future?

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Vaccines The End of Illness

• Figure 8.25 Alternative Pathways Toward Speeding
  Vaccine DevelopmentFigure 8.26 A New Look at
  DNA Vaccines
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