Complete Mycology for Medical Students

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MYCOLOGY Flagellates
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Most Yeast and Molds Are

• EUKARYOTIC
• (LACK CHLOROPHYLL) Unlike plants
• AEROBIC Metabolism
• Have a wide variant of pH
• Temperature is a basic variant between yeast and
  Mold

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Aspergillus Fumigatus

• Most common respiratory fungal infection in the
  United States
• Associated with Nosocomal Infections in Hospitals
• Can be cavitating

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Aspergillus Fumigatus
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Aspergillus Fumigatus
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Histoplasmosis

• Inhaled Hyphae Thin Branching
• Most asymptomatic
• May have flu-like night sweats
• Cavitating disease
• World wide distribution
• Caves Disease (BATS)
• Darlings DX

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Histoplasma Distribution
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Causing a Honey Comb Granulomatous
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Histoplasmosis

• TX- AMPHOTERICIN B

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BLASTOMYCOSIS

• Caused by inhalation of conidia of Blastomyces
  dermatidis
• 4Bs(broad based bud blasto)
• Difficult to see on CXR
• Aliasis
• Chicagos Disease
• Gilchrists Disease
• ENDEMIC TO OHIO AND MISSISSIPPI VALLEY
• Natural disease in Dogs and Horses

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YEAST FORM
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ROOM TEMP PHASE (fungal)
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BLASTOMYCOSIS

• TX- AMPHOTERICIN B
• Fluconazole

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Paracoccidomycosis

• P. Brasilensis
• Ulcerations of oral and nasal cavity
• Aliasis
• South-American Blastomycosis
• LUTZ-SPLENDORE-ALMEIDA
• DIMORPHIC YEAST
• INHIBITS Beta-estradiol
• TX-KETOCONAZOLE

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PARACOX-ORAL LESION
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Paracox of Lung
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HE of PARACOCCIDOMYCOSIS
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Sporotrichosis (MOLD PHASE)
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Lymphocutaneous Sporotrichosis
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Coccidomycosis

• Inhaled C. Immitis
• San Joaquin Valley Disease
• Pt experience mild febrile dx
• Spread by dust
• 40 do not get disease
• Test
• Spherulin
• Latex agglutination

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Coccidomycosis
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Coccidomycosis
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Cryptococcus

• Serous types A D
• PIGION EXCRETION
• Meningitis in debilitated patients
• Pulmonary can be asymptomatic to fulminant

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Cryptococcus neoforms
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Cryptococcus in India Ink
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Cryptococcus
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CryptococcusPigeon Feces
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CANDIDA- OPPORTUNISTIC
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Candida Esophagitis
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Dermal Candidia
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Typical Candida
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Vulvovaginal Candida
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Common in airway
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AMEOBA
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E-Histolitica
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ACANTHOAMEOB
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FLAGELATES

• Trichimonas Vaginalis
• Giardia Lambia

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Trichimonas

• Common Urogenital infection
• Motility by flagellum
• Sexual intercourse is primary mode of infection
• Prevelance
• 5-20 female
• 2-10male
• TX-Metronidazole

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Trichimonas
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Giardia

• Giardia has cause severe diarrhea and can be a
  flagellate of concern

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CILIATES

• Balantidium coli
• Coccidia

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Balantidium Coli

• Treatment
• TETRACYLINE
• IODOQUINOLMETRONIDAZOLE

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Coccidia
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Coccidia Lesion
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INDEPENDENT CLASS

• Microsporidia

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