Parkinson’s Disease : overview, symptoms, causes, treatment and diagnosis

1
Parkinsons Disease
2
Parkinsons Disease

• Parkinson's disease  is a degenerative disease
  of the central nervous system, which affects the
  motor system. The cause of the disease is mainly
  unknown, but it is due to the death of the cells
  in a portion of mid-brain. Collection of
  mis-folded protein in the brain witch can't be
  degraded due to certain mutation is other genes
  in the Lewy bodies of the neurons, which doesn't
  allow the motor neuron to work properly. Lewy
  bodies are abnormal circular structure which are
  found in the cytoplasm of the neuron
  cells.Parkinson's mostly occur to 1 percent
  population to person mostly above 65 years of
  age.
• In 2015, PD affected 6.2 million people, with
  117,400 deaths worldwide.
• Here, nerve cells don't produce enough of
  chemical, which is dopamine.
• With adverse of this disease, people have trouble
  in walking, talking or doing simple things
• Even there are events of depression, anxiety,
  stress etc.

3
Symptoms of Parkinson's disease

• Diagnosing the symptoms of Parkinson may be very
  difficult, as it can often be misguided with
  other diseases.
• Early symptoms may include
• Tremor or shaking
• Loss of smell
• Trouble moving or walking
• Trouble sleeping
• Small handwriting
• Stooping or hunching over (can't stand straight)
• Masked face
• Soft and low voice
• With increase in PD, certain chronic symptoms can
  be seen such as
• tremor of the hands, arms, legs, jaw and face
• bradykinesia or slowness of movement
• rigidity or stiffness of the limbs and trunk
• postural instability or impaired balance and
  coordination

4
Causes of Parkinson's

• Causes of Parkinson's are not known.
• But it is mostly caused by genetic factors or
  environmental conditions.
• Patient having a family history of PD, and
  exposed to certain toxic chemicals tend to have a
  higher than others.

5
Risk factors of Parkinson's disease

• In PD, males are more affected than females.
• Person of mostly above 65 years of age are more
  affected by PD.
• People exposed to pesticides and having a prior
  head injury are more risk to PD.
• Having a family person with PD, can be the most
  cause a risk forParkinson's disease

6
Treatments of Parkinson's

• There is no particular treatment for Parkinson's
  disease.
• As a initial treatment, certain antiparkinson
  medication L-DOPA (levodopa), with dopamine
  agonists being used once levodopa becomes less
  effective.
• As the disease progresses and neurons continue to
  be lost, these medications become less effective
  while at the same time they produce a
  complication marked by involuntary writhing
  movements.
• Diet and some forms of rehabilitation can show
  some effectiveness at improving symptoms.
• Surgery to place microelectrodes for deep brain
  stimulation has been used to reduce motor
  symptoms in severe cases where drugs are
  ineffective.1
• Evidence for treatments for the
  non-movement-related symptoms of PD, such
  as sleep disturbances and emotional problems, is
  less strong.

7
Diagnosis of Parkinson's

• There is no test to confirm Parkinson's disease.
• A doctor can confirm it by knowing the person's
  family history and by some neurological tests.
• Patients of Parkinson's undergo certain
  disturbance and emotional up downs. Support from
  family is the most important treatment for them.

8
CONNECT WITH US
Logon to www.lazoi.com Like us on
facebook https//www.facebook.com/LazoiTheLife Fo
llow us on Twitter https//www.twitter.com/lazoith
elife Follow us on Pinterest https//www.in.pinte
rest.com/lazoithelife