Bartter Syndrome

1
Bartter Syndrome
2
What is Bartter Syndrome?

• Bartter syndrome  is a rare inherited congenital
  defect that affects the kidneys. Bartter syndrome
  is caused by genetic mutations. Bartter syndrome
  is of two types - Neonatal Bartter syndrome and
  classic Bartter syndrome.
• Neonatal Bartter syndrome starts before birth.
  It can be very serious, even life threatening.
  Babies may not grow as they should in the womb,
  or they may be born too early. Classic Bartter
  syndrome usually starts in early childhood and
  isn't as severe as the antenatal form. But it can
  affect growth and cause developmental delays.
• The Bartter syndrome means that your kidneys are
  unable to reabsorb Sodium and you lose it in
  urine. If you have Bartter syndrome, you are
  likely to have hypokalemia or low potassium
  level, alkalosis or increased pH value of blood
  and low blood pressure.

3
What is Bartter Syndrome?
Continue

• Although another disorder called Gitelman
  syndrome is closely associated, it is milder than
  Bartter syndrome.
• The main effects of the Bartter syndrome are
  loss of Sodium in urine, rise in the level
  of aldosterone hormone, potassium wasting
  (excessive removal of Potassium from the body),
  hypokalemic alkalosis (abnormal acid balance in
  blood), and loss of Calcium in urine.

4
Symptoms

• What are the symptoms of Bartter syndrome?
• In most cases, neonatal Bartter syndrome happens
  during the twenty-fourth to thirtieth week of
  gestation with polyhydramnios or excessive
  amniotic fluid. Because of this, the infant will
  have condition known as polyuria or excessive
  urination and polydipsia or excessive consumption
  of fluids. If the infant does not receive
  requisite quantities of fluids, the complications
  could be life-threatening. Although these
  symptoms begin at the first two years after
  birth, they are most likely diagnosed only after
  the child is in schooling age.
• Symptoms of Bartter syndrome include
• Growth failure - Rate of weight gain is much
  lower than that of other children of similar age
  and gender

5
Symptoms
Continue

• Constipation
• Low blood pressure
• Kidney stones
• Muscle cramping and weakness
• Higher urination frequency

6
Treatment

• What is the cost for the treatment of Bartter
  syndrome in India?
• Which specialty of doctor is to be consulted for
  the treatment of Bartter syndrome in India?
• A pediatrician or a Nephrologist is to be
  consulted for the treatment of Bartter syndrome
  in India.
• Which hospital is to be preferred for the
  treatment of Bartter syndrome in India?
• Medanta - The Medicity hospital in India is to be
  preferred for the treatment of Bartter syndrome
  in India.

7
FAQ's

• 1. What are the causes of Bartter syndrome?
• Genes carry instructions that help your body
  work right. Genetic diseases can happen when
  there's a change in the gene (called a mutation).
• At least five genes are linked to Bartter
  syndrome, and they all play an important role in
  how your kidneys work especially in your ability
  to take in salt. Losing too much salt through pee
  (salt wasting) can affect how your kidneys take
  in other substances, including potassium and
  calcium.
• A lack of balance in these elements can lead to
  serious problems
• Too little salt can cause dehydration,
  constipation, and frequent peeing
• Too little calcium can weaken bones and cause
  frequent kidney stones
• Low blood levels of potassium can cause muscle
  weakness, cramping, and fatigue

8
FAQ's
Continue

• 2. What are the risk factors of Bartter
  syndrome?
• The risk factors of Bartter syndrome remain
  unknown, because the disease has its origins in
  genetic mutations of unknown causes.
• 3. What are the possible ways to prevent Bartter
  syndrome?
• There are no known prevention methodologies for
  Bartter syndrome, because the disease results
  from mutations of the genes.
• 4. How is Bartter syndrome diagnosed?
• Most kidney-related issues cause blood pressure,
  but Bartter syndrome causes low blood pressure.
  The above-mentioned symptoms could happen in
  people who take too many diuretics and laxatives.

9
FAQ's
Continue

• Medanta - The Medicity hospital in India,
  Bartter syndrome is diagnosed mainly by using
  blood tests and urine tests.
• 5. How is Bartter syndrome treated?
• If anybody have Bartter syndrome, a Nephrologist
  from Medanta - The Medicity hospital in India may
  recommend the following treatment procedures to
  cure.
• Dietary Changes
• Liberal amounts of Sodium and Potassium need to
  be included in the food consumed.

10
CONNECT WITH US

• Logon to
• www.lazoi.com
• Like us on Facebook
• https//www.facebook.com/LazoiTheLife
• Follow us on Twitter
• https//www.twitter.com/lazoithelife
• Follow us on Pinterest
• https//www.in.pinterest.com/lazoithelife