Anaplastic Astrocytoma : Causes, Symptoms, Diagnosis, Risk factor, Prevention Treatment in India

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Title: Anaplastic Astrocytoma : Causes, Symptoms, Diagnosis, Risk factor, Prevention Treatment in India


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Anaplastic Astrocytoma
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What is Anaplastic Astrocytoma?
  • The Anaplastic astrocytoma is defined as an
    uncommon cancerous tumor in the brain. These
    tumors form from several brain cells that are
    shaped as a star and are known as astrocytes.
    Cells like astrocytes develop the tissue that
    nears and shields other nerve cells that are
    present in the spinal cord and the brain.
    Together, all these cells are called glial cells,
    and the glial tissue is the tissue that they
    develop. Astrocytomas are one of the tumors that
    come from glial tissues and known as gliomas.
    Anaplastic astrocytoma is a kind of brain cancer.
    This Anaplastic astrocytoma comes in the class of
    high-grade gliomas that are persistently
    analogous gliomas and that take an improper
    clinical prediction. Anaplastic astrocytoma also
    lacks vascular multiplication.
  • The tumors that are caused in Anaplastic
    astrocytoma comprise of cells that are both
    normal and abnormal. The two kind of astrocytomas
    are low-grade astrocytomas and high-grade
    astrocytomas. The astrocytomas that have a
    tendency to grow slow are low-grade astrocytomas,
    whereas the ones which have a tendency to grow at
    a high pace are high-grade astrocytomas.

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Symptoms
  • What are the signs and symptoms of Anaplastic
    Astrocytoma?
  • The symptoms of anaplastic astrocytoma vary
    depending upon the exact location and size of the
    tumor. Most symptoms result from increased
    pressure within the brain. An anaplastic
    astrocytoma usually develops slowly over time,
    but may develop rapidly.
  • Increased pressure within the brain may be caused
    by the tumor itself or by blockage of the
    fluid-filled spaces in the brain called
    ventricles, which results in the abnormal
    accumulation of cerebrospinal fluid (CSF) in the
    brain. Symptoms commonly associated with
    anaplastic astrocytoma include headaches,
    lethargy or drowsiness, vomiting, and changes in
    personality or mental status. In some
    cases, seizures, vision problems, weakness of the
    arms and legs resulting in coordination
    difficulties may also occur.

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Symptoms
Continue
  • More specific symptoms relate to the area of
    brain where the tumor is located. Anaplastic
    astrocytoma may develop in any area of the
    central nervous system, although there is a
    strong preference for the large rounded portion
    of the brain (cerebrum) that occupies most of the
    skull. The cerebrum is divided into two halves
    known as the cerebral hemispheres. Anaplastic
    astrocytoma may develop in the frontal, temporal,
    parietal and occipital lobes of the cerebrum.
  • A tumor in the frontal lobe may cause memory
    problems, changes in personality and mood,
    and paralysis (hemiplegia) on the side of the
    body opposite of the tumor. Tumors in the
    temporal lobe may cause seizures, memory
    problems, and problems with coordination and
    speech. Tumors in the parietal lobe may cause
    difficulties with communication through writing
    (agraphia), problems with fine motor skills, or
    sensory abnormalities such as tingling or burning
    sensations (paresthesias).

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Symptoms
Continue
  • Tumors in the occipital lobe can cause visual
    loss.
  • Other common sites for anaplastic astrocytoma
    include the part of the brain that contains the
    thalamus and hypothalamus(diencephalon), the
    lower area of brain near the back of the neck
    that controls movement and balance (cerebellum),
    and the spinal cord. Tumors in the diencephalon
    region may cause headaches, fatigue, weakness of
    the arms and legs, vision problems, and hormonal
    imbalances. Tumors in the cerebellum may cause
    headaches, changes in personality or behavior,
    and balance problems. Tumors of spinal cord may
    cause back pain, sensory abnormalities such as
    tingling or burning sensations (paresthesias),
    weakness, and gait disturbances.

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Treatment
  • What is the cost of anaplastic astrocytoma
    treatment in India?
  • Which specialty of doctor is to be consulted for
    the treatment of anaplastic astrocytoma in India?
  • A neurologist is to be consulted for
    the treatment of anaplastic astrocytoma in India.
  • Which hospital is to be preferred for anaplastic
    astrocytoma treatment in India?
  • Medanta - The Medicity hospital in India is to be
    preferred for anaplastic astrocytoma treatment in
    India.

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FAQ's
  • 1. What is the cause of anaplastic astrocytoma?
  • The exact cause of anaplastic astrocytoma is
    unknown. Researchers speculate that genetic and
    immunologic abnormalities, environmental factors
    (e.g., exposure to ultraviolet rays, certain
    chemicals and ionizing radiation), diet, stress,
    and/or other factors may play contributing roles
    in causing specific types of cancer.
    Investigators are conducting ongoing basic
    research to learn more about the many factors
    that may result in cancer.
  • Astrocytoma occurs with greater frequency in
    certain genetic disorders including
    neurofibromatosis type I, Li-Fraumeni syndrome,
    and tuberous sclerosis. Except in these rare
    disorders, the vast majority of astrocytomas are
    not passed on to offspring with greater
    frequency. Researchers believe that some
    individuals may have a genetic predisposition to
    developing an astrocytoma. A person who is
    genetically predisposed to a disorder carries a
    gene (or genes) for the anaplastic astrocytoma,
    but it may not be expressed unless it is
    triggered or "activated" under certain
    circumstances, such as due to particular
    environmental factors.

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FAQ's
Continue
  • 2. What are the risks associated with anaplastic
    astrocytoma?
  • The only apparent risk of anaplastic astrocytoma
    may be the abnormal functioning of the brain. The
    working of the brain might be hampered because of
    anaplastic astrocytoma as a consequence of which,
    the tumor might form.
  • 3. What are the possible ways to prevent
    anaplastic astrocytoma?
  • To prevent anaplastic astrocytoma, there are no
    rules or guidelines to follow, because the causes
    of anaplastic astrocytoma are still not precisely
    found out.
  • 4. How is anaplastic astrocytoma treated?
  • The options of treatment are contingent upon size
    and type of anaplastic astrocytoma and to what
    extent anaplastic astrocytoma has spread
  • Surgery

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FAQ's
Continue
  • Additional surgery can treat the re-growth of
    tumor. Any different form of radiation,
    a chemotherapy drug or a group of some drugs are
    all the new ways of treatment of anaplastic
    astrocytoma. The purpose of radiation therapy is
    to lengthen the survival and has become an
    accepted component of treatment.
  • Temozolomide
  • It is also known as an oral chemotherapy drug to
    effectively treat the anaplastic astrocytoma.
    Although, the role of it as collateral of
    radiation therapy, has not still been revealed.

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