Xenith Advanced Fertility Centre with Dr. Mamta Dighe Gynecologist

1
Xenith Advanced Fertility Centre with Dr. Mamta
Dighe Gynecologist
Dr. Mamta Dighe is founder director of Xenith
Advanced Fertility Centre. She is one of the
first board certified IVF practitioners in India.
Such certification is mandatory in the US and
European countries for the practice of IVF.
Though not currently mandatory in India,
rigorous training in the field has conferred an
edge, which is otherwise difficult to acquire.
2
Prior to starting Xenith She was director of IVF
initiative at Deenath Mangeshkar Hospital and
has played a crucial role in the establishment of
IVF practice at Deenanath Mangeshkar
Hospital. Dr. Mamta Dighe Gynecologist has
helped several couples achieve their dream of
parenthood with wonderful testimonials from her
patients. She is well known for her academic
inclination and has been invited as faculty to
several national and international
conferences. What is ICSI? ICSI is very similar
to conventional IVF in that gametes (eggs and
sperm) are collected from each partner. The
difference between the two procedures is the
method of achieving fertilisation. In
conventional IVF, the eggs and sperm are mixed
together in a dish and the sperm fertilises the
egg naturally. However to have a chance that
this will occur, large numbers of actively
swimming normal sperm are required. For many
couples, the number of suitable sperm available
may be very limited or there may be other
factors preventing fertilisation, so conventional
IVF is not an option. ICSI has provided a hope
for these couples. ICSI refers to the laboratory
procedure where a single sperm is picked up with
a fine glass needle and is injected directly
into each egg (Figure ). This is carried out
in the laboratory by experienced embryologists
using specialist equipment. Very few sperm are
required and the ability of the sperm to
penetrate the egg is no longer important as this
has been assisted by the ICSI technique. ICSI
does not guarantee that fertilisation will occur
as the normal cellular events of fertilisation
still need to occur once the sperm has been
placed in the egg. Who is ICSI suitable
for? From a patient perspective, undergoing an
ICSI treatment cycle is exactly the same as a
conventional IVF cycle, and the same steps are
involved.
3
Circumstances in which ICSI may be appropriate
include When the sperm count is very low When
the sperm cannot move properly or are in other
ways abnormal When sperm has been retrieved
surgically from the epididymis (MESA/PESA) or
the testes (TESE/TESA), from urine or following
electro-ejaculation When there are high levels
of antibodies in the semen When there has been a
previous fertilisation failure using conventional
IVF. What does ICSI involve? From a patient
perspective, undergoing an ICSI treatment cycle
is exactly the same as a conventional IVF cycle.
Patients should however be aware of the risks
associated with ICSI. Stimulation of the ovaries
to encourage development and maturation of the
eggs Retrieval of the eggs Fertilisation of the
eggs and culture of the embryos Transfer of the
embryos back into the uterus. These steps are
described more fully under IVF. Ovulation and
egg retrieval To prepare for a procedure using
your own eggs, you must get daily shots and be
closely monitored for 2 weeks before the eggs are
collected. At home, you or your partner injects
you with gonadotropin or follicle-stimulating
hormone (FSH) to stimulate your ovaries to
produce multiple eggs. This is called
superovulation. After the first week, your
doctor checks your blood estrogen levels and uses
ultrasound to see if eggs are maturing in the
follicles. During the second week, your dosage
may change based on test results and ultrasound.
If follicles fully develop, you are given a
human chorionic gonadotropin (hCG) shot to
stimulate the follicles to mature. The mature
eggs are collected 34 to 36 hours later. This is
4
done using laparoscopy or needle aspiration
guided by ultrasound through the belly to the
ovaries. Sperm injection and transfer A glass
tool is used to hold an egg in place. A tiny
glass tube is used to put one sperm into the
egg. After culturing in the lab overnight, eggs
are checked to see if they've been fertilized.
After incubation, the eggs that have been
successfully fertilized or have had 3 to 5 days
to further develop are selected. One or more are
placed in the uterus using a thin flexible tube
(catheter) that is inserted through the cervix.
Your doctor will recommend how many embryos to
transfer, based on your age and other
information about you. The other embryos may be
frozen for future use. What To Expect After
Treatment The shots, monitoring, and procedures
for in vitro fertilization (IVF) can be
emotionally and physically demanding of the
mother. Superovulation with hormones requires
regular blood tests, daily shots, and frequent
monitoring by your doctor. Some of the shots can
be quite painful. These procedures are done on
an outpatient basis. They require only a short
recovery time. Your doctor may advise you to
avoid strenuous activities for the rest of the
day. Why It Is Done ICSI is used to treat severe
male infertility, as when little or no sperm are
ejaculated in the semen. Immature sperm collected
from the testicles usually can't move about and
are more likely to fertilize an egg through
ICSI. ICSI can be used even if a couple's
infertility is not related to a problem with
sperm. Some couples choose to try ICSI after
repeat in vitro fertilization has not worked.
5
ICSI is also used for couples who are planning to
test the embryo for certain genetic problems.
ICSI uses only one sperm for each egg. So there
is no chance the genetic test can be
contaminated by other sperm. How Well It
Works Used with in vitro fertilization and eggs
of good quality, ICSI often is successful for
men who have impaired or no sperm in the
ejaculate. ICSI (using sperm collected from the
testicles) produces an estimated 25 to 30 birth
rate.2
Risks Risks related to ICSI are the same as for
in vitro fertilization. Superovulation with hormo
ne treatment can cause
severe ovarian
hyperstimulation syndrome. Your doctor can
minimize the risk of this problem by closely
monitoring your ovaries and hormone levels during
treatment. The risk of conceiving a multiple
pregnancy is directly related to the number of
embryos transferred to a woman's uterus. Multiple
pregnancies are high-risk for both a mother and
her fetuses. There may be a higher risk of birth
defects for babies conceived by certain assisted
reproductive techniques, such as ICSI. Talk with
your doctor about these risks. Treatment success
versus the risk of multiple pregnancy For a woman
over age 35 to maximize her chances of conceiving
with her own eggs and having a healthy
pregnancy, she may choose to have more embryos
transferred than a younger woman would. But this
increases her risk of multiple
pregnancy. Because of the risks to the babies of
multiple pregnancy, experts recommend that you
limit the number of embryos transferred. Your
doctor will recommend a certain number of
embryos based on your age and other factors.
6
Women over 40 have a high rate of embryo loss
when they use their own eggs. Donor eggs may
work better these women. What To Think
About Doctors advise men who have little or no
sperm in their semen (not due to a blockage) to
have genetic testing before ICSI.1 ICSI is an
effective treatment for sperm-related
infertility. But it may have genetic risks.
Couples who have a chromosomal problem can seek
genetic counseling to learn their chance of
having a child with birth defects. If you and
your doctor are concerned about passing on a
genetic disorder to your child, talk to your
doctor about testing the embryo before it is
transferred to the mother. Frozen embryos are
often less expensive and less invasive for a
woman, because superovulation and egg retrieval
aren't needed. Xenith Advanced Fertility Centre
Is Situated At 307,8,9, third Floor, Wing B, GO
Square. Xenith Advanced Fertility Center Is Run
By Experienced Doctors With Specialities Such As
Gynecologist And Obstetrics. The Clinic Provide
Services In Cervical Cancer Vaccination,Pre And
Post Delivery Care,Vaginal Infection
Treatment,Well Woman Healthcheck,Obstetrics And
Antenatal Care,Laparoscopic Surgery Obs And
Gyn,Womens Health,Hysteroscopy,Menopause
Advice,Pcod Or Pcos Treatment,Gynae Problems,Pap
Smear,Laparoscopy Surgery,Diseases In
Pregnancy,Caesarean Section,Normal Vaginal
Delivery. For More Information You Can Contact
Us Block 30, East Patel Nagar, Rajendra Place,
New Delhi, Delhi 110008 (91)-7899912611 contact_at_e
lawoman.com https//www.elawoman.com/
7
Contact Form Ela Facebook
Ela Twitter
Ela Instagram
Ela Linkedin
Ela Youtube