Toxicology Testing Labs

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Toxicology Studies - 5 Top
Challenges for Animals in 2018
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Toxicology Studies

• The number of animals used in toxicology
  studies is continuously increasing. Every year
  millions of experimental animals are sacrificed
  in the name of scientific research. 
• Scientists across the world discuss about the
  pain, distress and death experienced by the
  animals during scientific experiments.
• To save the decreasing number of animals on this
  earth, many alternatives to animal testing are
  proposed.
• However, much needs to be done in this aspect and
  save animals from the clutches of scientific
  experiments.

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In this section, we discuss the 5 challenges
which the animal models are bound to face in the
upcoming years.
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1) The killing of animals in military and medical
training

• There have been constant efforts to stop the
  Defence Services from using goats and pigs in
  training their medical personnel, but the brutal
  killing of these animals is still prevalent.
• The animals are shot with firearms, stabbed and
  crippled during such training. And all this is
  happening when alternatives to animal
  testing exist.

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2) FDA regulations still mandate animal testing

• U.S. law now bans the use of animals in the
  chemical industry. It mandates the use and
  development of alternatives to animal testing.
  But, the Food and Drug Administration (FDA) lags
  on this. Current FDA regulations are age-old and
  havent been changed to support modern science.
• Many regulations still mandate animal testing
  before the clinical trials in humans. Though FDA
  and other federal agencies now acknowledge that
  animal tests fail to predict human outcomes in 95
  percent cases, they havent updated their
  regulations yet.

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3) Animal Research Organisations decrease
protection for animals in labs

• Organisations representing animal experimenters
  and their institutions aim to cut down
  protection for animals in laboratories.
• They seem to create an oversight system that will
  allow the laboratories to self-regulate.
• When federal laws and government enforcement are
  already weak, such a step from the organisations
  will further aggravate the problem of increased
  animal testing.

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4) Limited funds for Human-based research

• The government proposes to cut down the funds for
  EPA (Environmental Protection Agency).
• Lack of funds will inhibit EPA to develop modern
  safety assessment methods methods which do not
  use animals.
• This will put human-based research at stake and
  encourage the use of animals.

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5) Difficulty in procuring High-Quality Human
Cells and Tissues For Research 

• Though people understand the reasons for
  human-based research or why to use human cells
  and tissues, few know how these tissues are
  obtained for research. 
• The by-products of surgery are one source of
  human cells and tissues. Second, you can donate
  your tissue after death for research which
  otherwise would be discarded.
• However, many people are not aware of the second
  option. Thus, theres a need to educate the
  public and begin a discussion on the best
  practices for tissue procurement.

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Therefore, to save the future of human-based
research and decrease animal testing in
toxicology studies, the stakeholders of the drug
development process must come together and look
into these challenges seriously.
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