Surfactant

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Surfactant
Alfa Chemistry
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Overview
Surface tension
Two liquids A gas and a liquid, A liquid and a
solid
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Overview
Hydrophobic groups
Hydrophilic groups
Amphiphilic
A surfactant contains both a component and a
water-soluble component
Activity
Surfactants will diffuse in water and adsorb at
interfaces between air and water or at the
interface between oil and water, in the case
where water is mixed with oil. The
water-insoluble hydrophobic group may extend out
of the bulk water phase, into the air or into the
oil phase, while the water-soluble head group
remains in the water phase.?
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Overview
Hydrophobic tails
The hydrophobic tails of the surfactant ions
remain inside the oil because they interact more
strongly with oil than with water.
Hydrophilic Head
The hydrophilic heads of the surfactant
molecules coating the micelle interact more
strongly with water, so they form a hydrophilic
outer layer that forms a barrier between micelles.
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Nonionic Surfactant
Classification Of Surfactant
Anionic Surfactant
Cationic Surfactant
Amphoteric Surfactant
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Nonionic Surfactant
Water-solubility
The water-solubility of the oxygen groups is the
result of hydrogen bonding.
Hydrogen bonding
Hydrogen bonding decreases with increasing
temperature, and the water solubility of nonionic
surfactants therefore decreases with increasing
temperature.
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Anionic Surfactant
Sulfate
Phosphate
Sulfonate
Carboxylate
Ammonium lauryl sulfate
Sodium lauryl sulfate
Sodium laureth sulfate
Sodium myreth sulfate
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Cationic Surfactant
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Amine salt type
Quaternary ammonium salt type
Heterocyclic type
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Amphoteric Surfactant

• Phospholipids phosphatidylserine

• Phosphatidylethanolamine

• Sphingomyelins

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Solubilization
Wetting agents
Applications
Foaming and defoaming
Sterilization
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Solubilization
Electrolyte
Structural characteristics
Inorganic additives
Temperature
Organic additives
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Wetting agents
The purpose of adding surfactants is to increase
the adhesion and deposition of the drug, and to
increase the activity of active ingredient in the
presence of moisture.
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Foaming and defoaming
Oil-soluble celluloses
Indispensable emulsifiers
Steroid hormones
Suspending agents
Insoluble drugs
Foaming agents
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Sterilization
Preoperative skin disinfection
Mucosal disinfection
Device disinfection
Environmental disinfection
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