Granuloma Inguinale

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Granuloma Inguinale
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Granuloma Inguinale

• Granuloma Inguinale is a rare sexually
  transmitted disease (STD) that is caused by
  Klebsiella granulomatis bacteria. The most
  important risk factor for having this disease is
  unprotected sexual intercourse with multiple
  partners.One of the most important symptoms of
  this disease is the presence of painless, beefy
  red sores in the genital region or anus, which
  may bleed easily if injured.Antibiotics, like
  streptomycin and erythromycin are the mainstay of
  treatment for Granuloma Inguinale. These are
  typically recommended for a period of 3-4 weeks.

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What are the causes of Granuloma Inguinale?

• Granuloma Inguinale is caused by a rod-shaped
  bacterium which is known as Klebsiella
  granulomatis.The mode of transmission of this
  infection is through the sexual route Granuloma
  Inguinale is a sexually-transmitted infection.
  This bacterium is also known as Donovania
  granulomatis, and hence, Granuloma Inguinale is
  also known as Donovanosis.

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How is Granuloma Inguinale Diagnosed?

• An accurate diagnosis of Granuloma Inguinale
  might involve the following procedures and
  exams
• Complete evaluation of medical history, along
  with a thorough physical examination
• Genital examination to check for skin ulcers that
  are painless, likely to bleed, irregular in
  shape, or are fairly large in size
• Scraping or biopsy of the lesion It is one of
  the confirmatory diagnostic tests used for
  Granuloma Inguinale. The technique involves
  injecting a local anesthetic so that a tissue
  sample may be taken. The sample is stained with
  Wrights stain, which will turn Donovan bodies
  dark purple. Donovan bodies present in skin
  tissue can help confirm Granuloma Inguinale
  diagnosis

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Symptoms

• What are the Signs and Symptoms of Granuloma
  Inguinale?When an individual gets infected with
  the causative bacteria, it may take up to 12
  weeks for the symptoms of Granuloma Inguinale to
  become apparent.In many cases, the initial
  sores can go unnoticed, as they may not be
  painful or at a directly visible location.In
  affected individuals, initial signs are typically
  observed in the genital region.

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Symptoms
Continue

• The signs and symptoms of Granuloma Inguinale
  may include
• Presence of red bumps near the groin, genital or
  anal region
• Sores around the genitals or anus
• Bleeding from the sores
• Skin discoloration around the genitals
• Foul-smelling ulcers that are characterized by
  granulation tissue around the edges
• There can be associated fever due to the
  infection

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Treatment

• How is Granuloma Inguinale Treated?
• Oral antibiotics are most effectively used to
  treat Granuloma Inguinale, some of them are
  Ampicillin, Erythromycin, Tetracycline and
  Streptomycin
• These are typically prescribed for a duration of
  3-4 weeks
• The antibiotic course should be completed as
  prescribed by the doctor, even if the visible
  signs and symptoms of the condition disappear

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