Glomerular Disease

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Glomerular Disease
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Glomerular Disease

• Glomerular disease is a disorder of the kidneys.
  In this disease, the normal functioning of the
  kidneys gets disturbed and the chemical balance
  is not maintained in your blood and
  urine.Healthy kidneys extract out toxins and
  waste materials in the urine and retain red blood
  corpuscles and proteins in the blood itself. But
  in case of glomerular disease, toxins are
  retained in the blood, whereas red blood cells
  and proteins get filtered out in the urine.This
  disorder can be either acute meaning sudden
  occurrence or it can be chronic meaning it
  builds up over a period. To understand what
  glomerular disease is, it is important to
  understand the functioning of kidneys.

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Glomerular Disease
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• The kidneys are bean-shaped fist-sized
  structures which are located near the rib cage.
  They have small structures called nephrons, which
  are filtering units for blood.These nephrons
  are made up of glomeruli and tubules. The
  function of glomeruli is to filter wastes and
  excess fluids. The function of tubules is to
  convert wastes into urine. In glomerular disease,
  the filtration process of the blood gets
  affected.

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Causes of Glomerular Disease

• The causes of glomerular disease include 
• Genetic factors
• Thin basement membrane disease
• Post-infectious glomerulonephritis
• IgA vasculitis
• Lupus
• Severe post-infectious glomerulonephritis
• Fibrillary glomerulonephritis
• Mixed cryoglobulinemia
• Diabetic nephropathy
• Membranous nephropathy

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Causes of Glomerular Disease
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• Final stage of post-infectious glomerulonephritis
• IgA nephropathy
• Benign nephrosclerosis
• Primary amyloidosis
• Focal segmental glomerulosclerosis
• Minimal change disease

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Risks related with Glomerular Disease

• The risk factors for glomerular disease include
• Diabetes
• Kidney diseases and infections
• High blood pressure
• Obesity
• Age above 65

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Prevention

• To prevent the chances of glomerular disease
  follow
• Healthy lifestyle
• Avoid excessive usage of painkillers
• Regular exercise
• Dietary modification to suit problems like
  diabetes and high blood pressure

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How is Glomerular Disease diagnosed?

• The diagnosis of glomerular disease is done
  using the following methods
• Urine tests
• Blood tests
• Imaging tests
• Biopsy

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Symptoms of Glomerular Disease

• Some common symptoms of glomerular disease are
• High blood pressure
• Decreasing frequency of urination
• Fluid retention
• Swelling in lower legs, face, feet and abdomen
• Fatigue
• Blood loss in urine

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How is Glomerular Disease treated?

• The treatment of glomerular disease depends upon
  the severity of symptoms, the type of disease and
  the cause of the disease. Your doctor may
  recommend some medications that comprise
  ofSteroids - Immunosuppressant medications
  like steroids are used to treat glomerular
  disease. If the disease is found to be rapidly
  progressive, plasmapheresis is used to remove
  blood components responsible for
  inflammation.High Blood Pressure Management -
  Management of high blood pressure is important to
  decrease the damages onto the kidneys. Therefore,
  drugs are prescribed to decrease the amount of
  proteins in urine and to decrease the progression
  of glomerular disease.Kidney Transplantation -
  If the functionality of your kidneys is beyond
  restoration, your nephrologist may suggest a
  kidney transplantation procedure. In this, a
  healthy kidney from a donor is transplanted into
  you by surgical means.

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