Spherocytosis: Causes, Symptoms, Daignosis, Prevention and Treatment

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Spherocytosis
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Spherocytosis

• Spherocytosis is a condition in which an
  abnormality is caused in the red blood cell
  membrane. While healthy blood cells are shaped
  like flattened, indented discs, these abnormal
  membranes lead to sphere-shaped red blood cells
  and the premature breakdown of those cells.Red
  blood cells which are suffering from
  spherocytosis are basically smaller, rounder in
  shape, and more fragile than healthy red blood
  cells. The rounded shape causes the red blood
  cells to get caught in the spleen, where they
  easily break down.The different cases of
  spherocytosis can be mild with minor symptoms or
  severe with symptoms that quickly surface. These
  symptoms can be raised after the happening of
  some specific types of infections. Severe cases
  may be diagnosed in childhood, while those with
  mild symptoms may not be diagnosed until
  adulthood.

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Prevention

• Because spherocytosis is an inherited condition,
  it is not possible to prevent the disease.
  However, egular screening of individuals at high
  risk can prevent the risk of complications of the
  disease with early treatment.

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Symptoms of Spherocytosis

• Spherocytosis can cause 
• Yellowing of the skin or whites of the eyes i.e.
  known as jaundice
• Pallor
• Shortness of breath
• Fatigue
• Weakness
• In children, irritability and moodiness

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Treatment of Spherocytosis

• Just have a talk with your doctor about the best
  treatment plan for you. Treatment options
  includeFolic Acid SupplementationFolic acid
  1 mg/day and consideration for blood transfusions
  are suggested during the time of severe
  anemia. SurgerySurgical extraction of the
  spleen can treat the anemia. The abnormal shape
  of blood cells remains, but the blood cells are
  no longer destroyed in the spleen.Currently,
  meningococcal, Haemophilus, and pneumococcal
  vaccines are administered several weeks before
  splenectomy. Lifetime penicillin prophylaxis is
  suggested after surgery to prevent dangerous
  infections. The surgery is not advised for
  children who are under 5 years old. There is a
  lifetime risk of serious and potentially
  life-threatening infections.

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