Title: Surrogacy Medications
1- Welcome to Matrika Medicare
2Our body prepares an expectant mother by
releasing all the hormones necessary to carry a
child till its birth. It makes the uterus ready
for conception and then helps the embryo to be
stable and grow. But in the case of a surrogate
mother, she needs to be given medications before
and after the pregnancy to supplement the
required hormones released naturally to others.
Surrogate mothers in India receive same
medications that is being followed elsewhere in
other parts of the world. In the run up to this a
surrogate mother is given anti biotic to rule out
any possible pelvic infection. Once the vital
parameters of a surrogate mother are within the
reference range and all the screening process
gets completed, the surrogate receives medication
to start the treatment. The cycle of the
surrogate mother should match with the egg donor.
If the cycle of the surrogate mother doesnt
match with that of donor, the cycle is matched by
giving hormonal pills ie. birth control pills or
progesterone pills. Lupride acetate is the
medicine that need to be started from day 2 of
recipients cycle to supress her ovaries and
prevent hormonal interference in the pregnancy.
Birth control pills may be started about a
fortnight before Lupron. Injection of Lupron
completely shuts down the surrogates own cycle
medically and a synchronized cycle with egg donor
is started. Lupron should be stopped prior to
egg donation of the intended mother or egg donor.
3Hormonal injections/medications will be given to
enhance thickness of the endometrium. These
hormones are known as Estrogen and Progesterone.
Estrogen helps to thicken the lining of the
uterus and it can be taken orally or other
methods like injection or via abdomen skin patch
to get absorbed in the body. Once the lining
thickens and reaches critical thickness, hormone
progesterone is administered to make the
secretory changes in endometrium to make it
receptive for implantation and to maintain
pregnancy. Progesterone also can be given
subcutaneous, orally or as vaginal tablet. In the
journey towards Surrogacy weekly ultra sound and
blood tests will be performed to check the
thickness of the lining and hormonal level.
Ultrasound and Blood test confirming the level of
Progesterone helps IVF Specialist to understand
whether the uterus is ready for the embryo and
attained the optimum level of conception. On the
5th day of progesterone injection, blastocyst ie.
Day 5 embryo is transferred to the recipient. The
topic of Blastocyst embryo transfer will be
discussed separately. To maintain a stable
balance and help the uterus to retain the embryo,
Progesterone should be continued till beta hCG
test that confirms pregnancy and is continued
further if pregnancy test is positive. Once the
implant is successful and the pregnancy is
confirmed, Estrogen and Progesterone are
generally continued till first trimester. The
placenta then takes over hormone production and
these medications are not required routinely. In
some cases Aspirin is given orally to improve
implantation rates. The rest of the medication is
as per pregnancy similar to other pregnancies. A
surrogate mother will have to take vitamin
supplements and iron tablets during her pre natal
journey. She should have a healthy diet along
with medication with some exercise to keep her
fit and prepare suitably for the journey.
4- Side Effects of the hormone injections could be
bloating, irritability and tenderness of the
injection site. Some experience dizziness and
fatigue also with vaginal discharge. Oral tablets
can cause constipation, minor stomach upset.
There are many good Surrogacy treatment centres
in India where surrogate moms medication gets
full attention as every woman is different from
the other and needs a separate medication chart.
5We are available _at_ www.matrikamedicare.com or
call us in the numbers 011 4145 9114 or 91
9899481003. All your queries will be answered
within a short period of time.