How is Goserelin used for the treatment of Breast Cancer

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How Is Goserelin Used For The Treatment Of
Breast Cancer
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Goserelin (Brand Zoladex) is a medication used
for treating Breast Cancer. It is a hormonal
therapy drug that is given as an injection by a
doctor or a nurse in a hospital setting or a
clinic. Like all cancer medications, Goserelin /
Zoladex Injection can cause certain side effects.
Some of the more common goserelin / zoladex side
effects include
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• Sweating and/or hot flushes
• Changing moods
• Skin rash
• High levels of calcium in the blood
• Change in periods
• Tumour flares
• Hair thinning
• Bone thinning
• Headaches
• Pain in muscles and/or joints

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Even though, side effects that can be
life-threatening are rare. It is best to consult
with your doctor about all risks associated with
Goserelin. Another form of medication known as
Goserelin Acetate (Zoladex Impant) is an
artificial form of hormone that is used in men to
treat the symptoms of prostate cancer. It is
also used to treat breast cancer or endometriosis
in women. It works by preparing the lining of the
uterus for a surgery to correct uterine bleeding
or endometrial ablation.
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Goserelin (Brand Zoladex) comes in the following
doses Brand Zoladex 3.6 mg pre-filled
injections Brand Zoladex 10.8 mg pre-filled
injections Goserelin / Zoladex price information
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How can Goserelin (Brand Zoladex) be used to
treat Breast Cancer? Certain types of breast
cancer are dependent on a hormone called
oestrogen to grow and spread. Oestrogen is a
hormone that is mainly produced by the
ovaries. Goserelin works by switching off the
production of oestrogen hormone by altering the
hormone signals from the brain that directs how
the ovaries functions. This process is referred
to as ovarian suppression or ovarian ablation.
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Before Treatment Requirements To determine the
type of breast cancer that is dependent on
oestrogen to grow, your doctor would conduct a
test to check for oestrogen receptors using
tissue samples from a surgery or a biopsy. If
the tumour cells have receptors that are linked
with oestrogen hormone, then it is considered to
be oestrogen receptor positive and your treatment
with goserelin may begin.
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Certain tests may also be done to check for
progesterone receptors. The effects of hormone
therapy for people with progesterone positive
receptors is generally less successful. Such a
breast cancer types are also fewer. However, in
case of progesterone positive receptor breast
cancers, a specialist would determine whether
goserelin is the right treatment option for you.
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Treatment Effects Within the first three weeks
of receiving the goserelin injection, the
oestrogen amount in the body should reach levels
that are similar to that of a post-menopausal
woman. Additionally, you would also stop having
periods. Such changes are only temporary and will
likely last as long as you are receiving
goserelin.
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After Treatment Effects Once your treatment with
goserelin ends, the ovaries would start producing
oestrogen again and you would once again start
having periods within the first 3 months.
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Role of Goserelin / Zelodax in treating breast
cancer in post-menopausal women The current
standard treatment option for breast cancer in
post-menopausal women generally include
chemotherapy, tamoxifen medication and ovarian
ablation by surgery. The usage of goserelin in
managing the earlier stages of breast cancer only
offers an opportunity to avoid side effects
caused by cytotoxic chemotherapy.
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Can Goserelin be used to preserve fertility
during chemotherapy? Chemotherapy may damage the
ovaries and cause infertility in women.
According to certain studies conducted that
observed the effects of goserelin and
chemotherapy.
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It was found that goserelin may preserve the
ovaries during chemotherapy. This is because it
shuts down the oestrogen production or ovarian
suppression. However, ovarian suppression may
lower the effectiveness of chemotherapy. Hence,
the role of goserelin in preserving fertility in
women during chemotherapy is uncertain.
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Goserelin / Zoladex price information The
information provided on the page is meant for the
purpose of being helpful and educational. It
should not be considered as medical advice.
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