Transcription

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Transcription
R. C. Gupta Professor and Head Department of
Biochemistry National Institute of Medical
Sciences Jaipur, India
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Functions of different types of RNA

Structure Function
mRNA Single, uncoiled strand Transmits information from DNA, serves as a template for protein synthesis
tRNA Single strand folded back upon itself Brings amino acids to ribosomes for protein synthesis
rRNA Single strand folded into globular shape rRNA and proteins make up ribosomes
E M B - R C G
All types of RNA are synthesized from DNA
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Central dogma of molecular biology
E M B - R C G
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Transcription
Translation
DNA
RNA
Protein
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Transcription
E M B - R C G
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E M B - R C G
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Sense and antisense
E M B - R C G
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E M B - R C G
Roger Kornberg
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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Prokaryotic transcription
E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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Initiation phase
E M B - R C G
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Elongation phase
E M B - R C G
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Termination
E M B - R C G
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Eukaryotic transcription
E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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EMB - RCG
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Transcription of class I genes
EMB - RCG
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EMB - RCG
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Transcription of class II genes
EMB - RCG
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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Transcription of class III genes
EMB - RCG
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E M B - R C G
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Post-transcriptional modifications
E M B - R C G
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E M B - R C G
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Post-transcriptional processing of rRNA
E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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Post-transcriptional processing of hnRNA
E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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Splice sites
E M B - R C G
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E M B - R C G
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E M B - R C G
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Spliceosome
E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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Post-transcriptional processing of tRNA
E M B - R C G
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E M B - R C G
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Regulation of transcription
E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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E M B - R C G
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Inhibition of transcription
E M B - R C G
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E M B - R C G
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Thank you