Evolving role of zoledronic acid in early breast cancer

1
Evolving Role of Zoledronic Acid In Early
Breast Cancer
2
Most women diagnosed in the early stages of
breast cancer are likely to have a great
prognosis. It is also likely that they remain
disease free for several years after their
treatment ends. However, the side effects of
such treatments associated with bone issues are
also likely to have effect the patients bone
health in the long run. The bone loss
associated with breast cancer therapy like
endocrine therapy may contribute towards the risk
of osteoporosis and bone fractures in the long
run.
3
Several guidelines for treatment are now changed
to include the need for preserving bone health in
adjuvant therapy regimes and any measures
involved. Premature menopause induced by
chemotherapy can also increase the rate of bone
loss and reduction in bone mass density. This
may result in increased long-term risks of
osteoporosis and fracture.
4
Zoledronic / reclast acid cost information Zoledr
onic Acid infusion alters bone formation and
breakdown in the body to slow down the rate of
bone loss and possibly prevent bone
fractures. Bisphosphonates have been used for
the treatment of osteoporosis and bone metastases
in patients diagnosed with advanced stage
cancers. In respect to treating such diseases
in breast cancer cases, an intravenous
bisphosphonate known as zoledronic acid is
believed to play an important role.
5
Generic Zoledronic Acid Brand Reclast, Zometa,
Aclasta How does Reclast infusion work A
patients risk of fractures is directly
associated with bone mass density and clinical
risk factors. As such, prevention of bone loss
during treatment is proven to be beneficial for
reduction of long-term fracture risk.
6
In case of post-menopausal women suffering from
osteoporosis, bisphosphonates such as reclast
medication have generally been used for the
prevention and reversal of age-related bone
loss. In a recent clinical trial involving
post-menopausal women with early hormone
responsive breast cancer who were being treated
adjuvant endocrine therapy. One group was to
only receive the endocrine therapy while the
second group would also receive Zoledronic Acid
infusion.
7
Patients who only received endocrine therapy had
below baseline levels bone mass density. While
the patients who also received Zoledronic Acid
injection had improved levels of bone mass
density. Therefore, the use of bisphosphonates
as an adjuvant therapy for all post-menopausal
women with early breast cancer should be
considered.
8
Treatment with adjuvant bisphosphonates like
Zoledronic Acid can modestly cause the reduction
of the risk of outcomes related to breast
cancer. Zoledronic Acid / Reclast Side
Effects Some side effects of zoledronic acid /
reclast include
9

• Pain in jaw
• Numbness and/or swelling
• Problems in kidneys, signs swelled feet
  ankles, tiredness, shortness of breath, little or
  no urine
• Pain in joints, muscles and/or bone
• Low levels of calcium in blood, signs numbness,
  a tingly feeling around fingers, toes or mouth
  and/or muscle spasms

10

• Common side effects may include
• Fever and/or other symptoms of a flu
• Pain in limbs
• Headaches
• Feeling tired
• Difficulty in breathing
• Nausea, vomiting, constipation and/or diarrhea

11
Zoledronic acid cost information The information
provided on the page is meant for the purpose of
being helpful and educational. It should not be
considered as medical advice.     Reclast,
zoledronic acid, aclasta, reclast infusion,
zoledronic acid infusion, reclast side effects,
zoledronic acid side effects, zoledronic acid
cost, reclast cost, zoledronic acid injection,
reclast medication, reclast injection, zoledronic
acid brand name, zoledronic acid osteoporosis,
reclast infusion for osteoporosis, how does
reclast work, side effects of zoledronic acid
12
Contact Us Website www.CancerCurePharmacy.com E
mail CustomerCare_at_CancerCurePharmacy.com