ikgdar 500mg injection - PowerPoint PPT Presentation

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ikgdar 500mg injection

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Ikgdar 500mg is a anticancer medicine which prevents the growth and spread of cancer cells in the body. – PowerPoint PPT presentation

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Title: ikgdar 500mg injection


1
Ikgdar 500 mgRituximab injection uses,dose,side
effects,price India
  • MILLION HEALTH PHARMACEUTICALS

2
DESCRIPTION
  • Ikgdar 500mg is a anticancer medicine which
    prevents the growth and spread of cancer cells in
    the body. 
  • Ikgdar 500mg injection also indicated for the
    treatment of Non- Hodgkins lymphoma or chronic
    lymphocytic and with combination with another
    anticancer drugs like methotrexate is used for
    rheumatoid arthritis symptoms in adult treatment.
  • Ikgdar 500mg with steroid regimen combination is
    given for the treatment of some rare disorders
    which cause blood vessels and other tissues
    inflammation in the body.

3
INDICATION
  • Ikgdar 500mg injection and hyaluronidase human
    injection are given alone or combination with
    another drugs to treat certain types of
    non-Hodgkin's lymphoma and chronic lymphocytic
    leukemia (cancer start in WBC). 
  • Ikgdar 500mg injection is also used with
    methotrexate (Otrexup, Rasuvo, Xatmep, others)
    for the treatment rheumatoid arthritis symptoms
    in adults that have been already treated with a
    some type of regimen known as tumor necrosis
    factor (TNF) inhibitor. 

4
Rheumatoid arthritis
5
PHARMACODYNAMIC
  • new type of "targeted" cancer treatment and an
    integral part of the body's immune system.
    Naturally the body build antibodies in along with
    to an antigen which has entered the body and
    attach to the antigen for destruction by the
    immune system. An essential cells only aimed by
    monoclonal antibiotics, they may leads to less
    toxicity to healthy cell and it is usually
    treatment recommended only for cancers in which
    antigens (and the respective antibodies) have
    been already identified.

6
PRODUCT DETAILS
  • Brand IkgdarIngredients Rituximab Strength
    500mg Manufactured Emcure pharmaceuticalsPac
    kage injection

7
PHARMACOKINETICS
  • ABSORPTION
  • Not availableDISTRIBUTION
  • volume of distribution is 3.1 LMETABOLISM
  • Ikgdar 500mg injection metabolized by human
    antimurine antibody production.EXCRETION
  • not available The half life of NHL is 22 days and
    for RA is 18.0 days, GPA and microscopic
    polyangitis is 23 days

8
DOSAGE MANAGEMENT
  • Ikgdar 500mg is recommended to administer only
    through intravenous infusion not by IV push or
    bolus.ADMINISTRATION
  • Take an Ikgdar 500mg injection amount and diluted
    to final concentration of 1 mg/ml upto 4 mg/ml as
    infusion (containing either 0.9 Nacl or 5
    dextrose in water). Invert gently the bag and mix
    the solution. Dispose unused drug left in vial.
  • OVERDOSAGE
  • If the patients had high dose of Ikgdar
    500mg then seek immediately to the emergency
    department or poison control help line. Please
    consult the doctor for further clarification.

9
DRUG INTERACTION
  • Ikgdar 500mg injection drug interaction has
    limited data is available at present. Combination
    with fludarabine or cyclophosphamide has no
    effects in pharmacokinetics in CLL patients.
    Combination with methotrexate had no effects in
    pharmacokinetics.

10
CONTRAINDICATIONS
  • Hypersensitivity or murine proteins. Active
    severe infectons in rheumatoid arthritis
    Uncontrolled cardiac disease.

11
PREGNANCY
  • CategoryC animal studies reproduction shown an
    adverse effect on the fetus. The drug has no
    sufficient and well controlled studies in humans,
    using in pregnant women benefits by warrant use
    of the drug.

12
LACTATION
  • Ikgdar 500mg excreted into human milk is unknown.
    Due to the drug belongs to large protein
    molecule, no information is available. Women
    should not breast feed during Ikgdar
    500mg treatment and 12 months following last dose.

13
STORAGE
  • Store at 2C 3CUse the drug before expiry
    dateProtected from direct sunlightDo not freeze
    or shake.Keep away from the childernsDiscard
    the unused drug by asking the advice from doctor
    or pharmacist.

14
MISSED DOSE
  • If a dose missed to take at the time then have it
    suddenly before next dose timing, if time reach
    for next dose, then skip missed dose and continue
    and continue the regular schedule. Do not have 2
    dose at a same time.

15
CONTACT US
  • EMAIL ID  millionhealthpharmaceuticals_at_gmail.com
  • PHONE NO  91-9940472902
  • WEBSITE URL  https//millionpharma.com/ikgdar-500
    mg.php
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