EVEROLIMUS EVERTOR 10MG - ANTICANCER DRUGS | BIOCON | MHP

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EVEROLIMUS EVERTOR 10MG - ANTICANCER DRUGS
BIOCON MHP

• Million Health Pharmaceuticals

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DESCRIPTION

• Evertor 10mg tablet consist of an active
  ingredient known as Everolimus which is intrude
  with growth of cancer cell and process is slows
  down.Evertor 10mg tablet is not a curable
  medication, which is helps to slow their
  spreading in to the body.

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EVERTOR PRESCRIBING INFORMATION

• Primarily Evertor  10mg tablet indicated for the
  treatment kidney carcinoma Breast carcinoma Brain
  carcinoma Everolimus is also indicated in various
  advanced stage cancer in stomach, intestines or
  pancreas.

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EVERTOR MECHANISM

• Everolimus is an inhibitor of mTOR, joins at high
  compatibility to FK506 binding protein 12, via
  producing drug complex that inhibits the
  productive of mTOR. This inhibition reduce the
  activity of effectors downstream, which may leads
  to stoppage of cell progression from G1 into S
  phase, Finally causes cell growth arrest and
  apoptosis

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 kidney carcinoma
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aDME PROCESS

• ABSORPTION
• The maximium plasma concentration time of
  Everolimus reaches within 1 to 2 hours.
• DISTRIBUTION
• Albumin human plasma protein bound of 74.
• METABOLISM
• In hepatic Everolimus metabolism is occurred,
  which is a substrate of CYP3A4. The metabolites
  of Everolimus in 3 process Three
  monohydroxylated metabolite, Two hydrolytic rings
  opened products, Phosphatidylcholine conjugate of
  Everolimus.
• ELIMINATION
• half life period of Everolimus is 30 hours The
  elimination primarily via 5 in urine the parent
  compound has been detected in urine or feces.

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PRODUCT DETAILS

• Brand Evertor Ingredients Everolimus Strengt
  h 10mg Manufactured Biocon Package 10
  Tablets in a strip 

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DOSAGE REGIMEN

• In breast cancer, renal cell cancer, pancreatic
  cancer, Neuro endocrine cancer The prescribed
  dosage is 10mg should be taken as a single dose.
  In Brain or intracranial cancer The prescribed
  dosage of Evertoras 10mg a single dose. is
  4.5mg/m2 given orally In pediatric The pediatric
  dosage of Evertor as a single dose in brain or
  intracranial tumor is 4.5mg/m2 should be given
  orally.

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OVER DOSAGE

• The over dosage of Everolimus is limited, If over
  dosage occurs patient must be provide with
  supportive measures. And monitor evidence of
  toxicity in Everolimus over dosage
• WHEN TO TAKE THE DRUG EVERTOR
• Evertor 10mg tablets should be given with or
  without food.

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EVERTOR CAUSED SIDE EFFECTS

• Hypersensitivity reactions Lymphomas other
  malignancy Serious infections Kidney graft
  thrombosis Hepatic artery thrombosis
  Nephrotoxicity Hyperlipemia Angioedema
  Interstitial lung disease Thrombocytopenia Male
  infertility Proteinuria New commencement of
  diabetes

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SAFETY PRECAUTIONS

• LYMPHOMAS
• Developed hazard of skin cancers, patient may
  protect from UV light
• SERIOUS INFECTIONS
• Patients getting Evertor 10mg have severe risk of
  achieve various infections related to bacteria,
  virus, and fungiHEPATIC ARTERY THROMBOSIS
• Evertor 10ng tablet therapy should not be
  recommended in In liver transplant patients,
• EMBRYO FETAL TOXICITY
• using Evertor 10mg in pregnancy condition Causes
  fetal damage

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NEPHROTOXICITY

• While using Evertor 10mg tablet in renal impaired
  patients Renal function should be monitored
  frequently drug use with caution
• INTERSTITIAL LUNG DISEASE
• In Evertor 10mg therapy interstitial lung disease
  occur Blood glucose level should be monitored

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DRUG INTERACTION

• Evertor  10mg tablet interaction with strong
  inhibitor of CYP3A4, or P-gp, cause reducing the
  efflux of Everolimus and high plasma
  concentration of Everolimus. Interaction of
  Evertor with strong CYP3A4 inducers, will
  increasing the disclosure of Everolimus.
  Combination ofEvertor with cyclosporine will
  increasing the AUC level of Everolimus
  frequently. 

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PREGNANCY LACTATION

• Pregnancy category of Everolimus C In patients
  Evertor is used only after knowing the benefits
  to the mother exceed the risk to fetus. Breast
  feeding should not be suggested

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CONTRAINDICATION

• If patients are contraindicated to the components
  present in the Evertor 10mg tablet. Some
  anaphylactic reaction occurs.

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MISSED DOSE

• If the dose is missed, consult with healthcare
  practitioner and follow the instructions given by
  them. Thereby missed dose should be avoid and
  follow the regular dosing schedule.

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CONTACT US

• MOBILE NO  91-9940472902
• E-MAIL   millionhealthpharmaceuticals_at_gmail.com
• WEBSITE URL   https//millionpharma.com/evertor.p
  hp