Pomahope 2mg capsules | Pomalidomide |Millionpharma

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Pomahope 2mg capsules Pomalidomide
Millionpharma
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POMAHOPE 2MG

• DESCRIPTION
• Pomalidomide is sold under the brand
  name Pomahope 2mg and it belongs to
  anti-neoplastic drugs
• Pomahope 2mg is doable as orally bioavailable
  thalidomide derivative associated with numerous
  therapeutic activities such as immune
  modulatory, anti-angiogenesis, anti-neoplastic.
• Pomahope 2mg combination with dexamethasone will
  cause liver injury

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POMAHOPE 2MG

• Pomahope 2mg price in india
• Pomahope price in india
• Pomahope 2mg side effect
• Pomahope uses
• Pomahope 2mg
• Pomahope 2mg capsules

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CLINICAL USE

• The primary indication of Pomahope 2mg is used in
  the treatment of Multiple Myeloma condition.
• In this condition, Pomahope 2mg is used by
  combining with dexamethasone.
• Pomahope 2mg capsules are applicable in
• Previously the Patients treated with two
  treatment such as proteasome inhibitor
  Lenalidomide.
• Patients who are suffered with disease
  progression condition
• Pomahope 2mg capsules treatment should be
  followed within 60 days in patients who are
  concluded the last treatment.

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MECHANISM OF ACTION

• Pomahope price in india has three primary
  pharmacological activities against cancer cells.
• Pomalidomide includes in the way cancer
  proliferation and provoke the apoptosis of cancer
  cells.
• Pomalidomide enhance the T cell natural killer
  cells interceding immunity inhibits the
  formation of pro inflammatory cytokines from
  monocytes.
• Pomalidomide forbid the new cell formation. The
  binding of Pomalidomide to active site of
  targeted cell causes inhibition of ubiquitin
  ligase action.

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POMAHOPE 2MG

• Brand  Pomahope
• Ingredients  Pomalidomide
• Strength  2mg
• Manufactured  Abbott
• Package  21 capsules

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PHARMACOKINETICS

• The time to high serum concentration of
  Pomalidomide is reaches between 2 to 3 hours.
• It should be administered with or without food.
  Hence No effect of food should be produced
• Volume of distribution of Pomalidomide is between
  62 138L in steady state.
• The Pomalidomide distribution by 67 of serum
  level at after 4 hours of drug intake.
• human plasma protein by bounding range of 12
  44.
• Hepatically mediated through CYP1A2, CYP3A4 is
  Pomalidomide is metabolized.
• Pomalidomide clearance value is 7 to 10L/hr.
• Doses are excreted via urine 73 feces 15
  respectively.
• Doses are excreted as an unchanged form via urine
  2 feces 8.
• Pomalidomide half-life period is 9.5 hours.

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DOSAGE MANAGEMENT

• During multiple myeloma malignancies
• The dosage recommendation of Pomahope 2mg is 4mg
  should be administered as a single dose for 1 to
  21 days of successive 28-day cycles.
• Pomahope is combined with dexamethasone with low
  dose.
• Administrate Dexamethasone on day 1, 8, 15 22
  of each 28-day cycle.
• The prescribed dose of dexamethasone is 40mg
  should be administered the patient having weight
  about 75kg.
• The prescribed dose of dexamethasone is 20mg
  given for patients weight Greater than 75kg
• Dosage alteration during hematological
  toxicities

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Neutropenia

• ANC lt500/mcL Pomahope price in india treatment
  should be postponed and check the CBC weekly.
• ANC 500/mcL Pomahope side effect therapy
  should be continued by 3mg/day
• For each successive drop lt500/mcL Pomahope 2mg
  should be postponed.
• ANC 500/mcL Continue the Pomahope uses therapy
  with 1mg/day.
• Thrombocytopenia
• Platelets count lt25000/mcL Pomahope therapy
  should be postponed and check CBC
• Platelets count 50000/mcL 3mg of Pomahope
  should be taken daily
• With strong CYP1A2
• Pomahope combined with CYP1A2 substrates causes
  increasing the plasma concentration of
  Pomalidomide and leads to elevate the risk of
  Pomalidomide. In renal damaged patients
• In severe renal impaired patients, the suggested
  dose of Pomahope is 3mg per day.
• In hepatic impaired patients
• The advised dose is 3mg/day in severe
  condition, the suggested dose is 2mg/day given
  for mild to moderate patients.

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CONTACT US

• MOBILE NO  91-9940472902
• EMAIL  millionhealthpharmaceuticals_at_gmail.com
• WEBSITE URL  https//millionpharma.com/pomahope-2
  mg.php