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1
Lenalidomide - Lenangio 25mg tablet online
Myapplepharma
2
  • Lenangio 25mg is belongs to anticancer medication
    which contains Lenalidomide as an active
    substance which belongs to thalidomide analogue.
  • Lenangio 25mg CAPSULE  is used to the disease
    condition by combining with dexamethasone.
  • Lenangio 25mg consist of some other
    pharmacological activities like immuno modulatory
    anti-angiogenesis.
  • Lenangio 25mg capsule price in india  is a
    prescription drug that can only use under the
    supervision of medical oncologist.

3
INDICATION
  • The indications of Lenangio 25mg areLenangio
    combination with dexamethasone is indicated to
    treat the patients suffered from multiple
    myelomaLenangio is indicated for the patients
    having transfusion-dependent anemia because of
    intermediate 1 risk myelodysplastic syndrome
    along with deletion 5q cytogenetic abnormality
    without or without addition cytogenetic
    abnormalities
  • Lenangio is used to treat the patients with
    mantle cell lymphoma in which its used whose the
    disease was relapsed or progressed after two
    before treatment, especially the disease not
    response with the bortezomib therapy.

4
  • ThrombocytopeniaDrops to lt50000/mcL, treatment
    should be interrupted. Back to gt or equal to
    50000/mcL, follow the Lenangio of 5mg per day.
  • NeutropeniaDrops to lt500/mcL, treatment should
    be delayed. Back to gt or equal to 500/mcL,
    treatment should be follow to 5mg per day.
  • Multiple myelomaIn this disease, concomitant
    use of dexamethasone with Lenangio. The regular
    dose of Lenangio is 25mg should be given as once
    in a day on day 1 to 21.
  • The dose of dexamethasoneDexamethasone 40mg
    should be continued on day 1 to 4, 9 to 12 17
    to 20 of each period of 28-day cycles. Patient
    with greater than 75 years, dexamethasone 20mg
    should be prescribed on day 1, 8, 15, 22.

5
MECHANISM
  • Lenangio 25mg capsule involves in the prudence of
    tumor and factor alpha arrangement, that
    reinforcement the T-cells and leads to lessening
    plasma levels of cytokines vascular endothelial
    growth factor and fundamental fibroblast growth
    factor. Lenangio 25mg capsule price in india  is
    moreover engaged with the stave off
    angiogenesis.Lenalidomide is furthermore
    authorize G1 cell cycle capture and apoptosis of
    ruinous cells.

6
PHARMACOKINETICS
  • Absorption Absorbed rapidly with peak plasma
    concentration is between 0.625 and 1.5 hrs.
    combining with food will not change the prolong
    of absorption but dose decrease in Cmax. 
  • Distribution Bounding of plasma protein is
    30 
  • Metabolism Mainly metabolized in two
    metabolites is hydroxy-lenalidomide and
    N-acetyl-lenalidomide. 
  • Excretion Primarily eliminated in renal route
    and the dose excreted via urine 90 and feces 4
    and half-life is 3hrs

7
DRUG INTERACTION
  • Interaction of Lenangio 25mg with digoxin leads
    to increased concentration of digoxin causes
    increased risk of adverse effects related to
    digoxin.Interaction of Lenangio 25mg capsule
    with Erythropoietic agents, cause to produced
    rises in risk of thrombosis. Discuss with the
    patients prior to starting this combination
    treatment.
  • Interaction of Lenangio 25mg price in india with
    warfarin, will produce increased exposure of
    hemorrhage disorders. check the INR value
    prothrombin time.

8
CONTRAINDICATION
  • When pregnancy period the drug is contraindicated
    The patients are contraindicated to
    hypersensitivity reaction and the Lenangio 25mg
    price in india  component.

9
OVER DOSAGE
  • Over dosage of Lenangio 25mg capsule  will cause
    neutropenia thrombocytopenia as mainly common
    side effects. Give the patient general supportive
    treatment. check the blood cells counts regularly
    during the treatment.

10
CONTACT US
  • Phone Number
  • 91-9987711567
  • Email ID
  • applepharmaceutical_at_gmail.com
  • Address
  • Apartment No.304 A Wing, Shiva Shakthi chs
    ltd, JP Road, Near Apna Bazar,Andheri(West),Mum
    bai - 400058.Maharashtra.
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