HALO1618 Authentic NMN by Sinclair Laboratories

1

• HALO1618 Authentic NMN by Sinclair Laboratories

NMN.health
2
Introduction - What is NMN? The Science Behind
NMN Popular Research
Health Advantages of Taking NMN Supplement Boost
NAD Levels Endurance DNA Repair Weight
Aging HALO1618 Authentic NMN by Sinclair
Laboratories FAQ HOW OFTEN SHOULD I TAKE
HALO1618 NMN? WHICH LAB HAS THE HALO1618 NMN BEEN
TESTED ? WHY DO YOU USE ERYTHRITOL? About
Sinclair Laboratories
Contents
3
INTRODUCTION
WHAT IS NMN? NMN is the short name for
Nicotinamide Mononucleotide. Its a form of
Vitamin B3, and occurs naturally in tiny amounts
in some fruits and vegetables. Its right there
in tomatoes, avocados, cucumbers and some
others. When you take NMN, it increases your
bodys levels of a molecule called NAD which
your body then uses to repair cellular damage,
and increases energy levels. Nicotinamide
mononucleotide (NMN) or Nicotinamide-1-ium-
1-ß-D-ribofuranoside 5'-phosphate is a type of
bioactive nucleotide which is naturally formed
by the reaction between a phosphate group and a
nucleoside containing ribose and nicotinamide
1. Generally, it exists in two anomeric forms
namely alpha and beta.
4
The Science Behind NMN
In human cells, NMN is available as a source of
cellular energy. Not long ago, this molecule was
only known for its activity as an intermediate in
nicotinamide adenine dinucleotide (NAD)
biosynthesis. During this biosynthetic process of
NAD, NMN acts as an important substrate for
enzymes like nicotinamide mononucleotide
adenylyltransferase 1 or NMNAT 1 of nuclear
origin and NMNAT 3 of mitochondrial origin that
helps in the enzymatic conversion to NAD in
humans. Recently, preclinical studies have
demonstrated diversified pharmacological
activities of NMN in cardiac and cerebral
ischemia, Alzheimers disease, diet- and
age-induced type 2 diabetes, and obesity, all of
which are linked up to the deficiency of NAD.
Camacho-Pereira et al. have shown that an
increased level of NAD consuming enzymes e.g.,
NAD dependent acetylase (Sirtuins), poly
ADP-ribose polymerase (PARP), NADase (CD38)
contribute to the decline of NAD with age.
5
Popular Research
Scientists have discovered that as we get older,
our NAD levels steadily decrease, and by the
time we get to our late 70s 80s, our NAD
levels appear to be much lower, than those of
younger people. The science is starting to
clearly show a definite correlation between
falling NAD levels and an age-related decline in
health wellness. In 2013 Harvard researchers
published a study, where they were able to
reverse some parts of aging by treating old mice
with NMN, a direct NAD precursor
supplement. After ten days of treatment, key
biometrics markers measured resembled those of
much younger mice. For the first time, we have
real evidence that some aspects of aging may be
reversible. In 2017 the same team published a
follow-up article. It demonstrated a new
understanding of how NAD is not only used to
repair damaged DNA but how it also stimulates the
repair process. It does this by blocking another
protein called DBC1 that interferes with the
PARP-1 DNA Repair enzymes.
6
Health Advantages of Taking NMN Supplement

• NMN is an entirely natural compound found in our
  bodies. Various food sources also contain this
  compound in minuscule amounts. Edamame which has
  one of the higher contents, only show less than
  1.9mg/100g. NMN is a direct and potent NAD
  supplement. Mice given an oral supplement of NMN
  showed increased liver NAD levels in just 10
  minutes and showed an increase in muscle tissue
  by 30 minutes.Increased NAD levels stimulate
  energy DNA repair and SIRTUIN activity. SIRTUINS
  are the longevity-genes shown to be active during
  caloric restriction and life-extension in many
  animal models.
• NAD helps to breakdown food like sugars into
  energy.
• Promotes Healthy Cardiovascular Function.
• DNA Repair - NAD is used to repair broken DNA
  strands.
• SIRTUIN Activator - NAD is required for our
  longevity genes to work.
• NMN is THE compound used by Harvard Scientists to
  reverse some signs of aging tissue in mice that
  started the rush to NAD supplements.

7
BOOST NAD LEVELS
NMN has an important effect on the production of
cellular energy because it is a critical
component in the production of NAD. Levels of
NAD are of critical importance for keeping
mitochondria, the bodys powerhouse, working at
peak, youthful levels. Because of its importance
as a NAD intermediate, active supplementation
with NMN increases the concentration of NAD in
the body, providing a readily available supply
of this important nutrient for the amelioration
of age-associated diseases and conditions 1.
8
Endurance
Decreased physical endurance and muscle strength
are often considered to be inevitable symptoms
of the normal aging process. However, recent
animal research indicates that NMN can prevent
these declines in aging mice. In fact, one study
found that consumption of NMN enhanced endurance
and muscle strength in aged mice to such a
degree that they became as healthy as their
much-younger peers! 2
9
DNA REPAIR
DNA damage is thought to contribute to the rising
risk of cancer as we age and is implicated in
various age-related diseases. Our cells have the
innate ability to repair that damage, but,
unfortunately, that ability to repair declines
as we grow older.
In a 2017 study, the researchers identified that
the metabolite NAD, which occurs naturally in
every single cell in our body, has a critical
role in DNA repair by regulating the
protein-to-protein interactions involved in that
process.Your DNA fills in as the outline for your
body physiological capacity. NMN avoids
antagonistic changes in quality articulation by
fixing harmed DNA.
10
AGING
Perseverance and muscle quality are not by any
means the only physical side effects affected by
the aging procedure, digestion, energy levels,
body mass, insulin affect-ability, and vision
are likewise unfavorably influenced by the aging
process.
As researches have shown that low levels of NAD
leads to aging, NMN supplementation has been
found to stifle age-related weight gain, upgrade
digestion, improve insulin affect-ability and
plasma lipid levels. These impacts features the
restorative capability of the NMN supplement and
as a beneficial remedy for anti-aging among
humans.
11
HALO1618 AUTHENTIC NMN BY SINCLAIR LABORATORIES
HE EXTRAORDINARY CELLULAR AGE-REVERSING MOLECULE
FORMULATED ENGINEERED TO BE THE MOST POWERFUL
AND EFFECTIVE NMN ON THE MARKET. We invite you
to take HALO1618 The Authentic NMN, increase your
NAD levels and live healthier! Sublingual
tablets offer the most effective delivery system
for NMN. By dissolving our tablets under your
tongue, the NMN is supplied directly to the
bloodstream. The tablets are chewable if you want
to speed up the process. We use a formula
called Erythritol X to improve absorption of the
NMN into the bloodstream. Erythritol is a
natural sweetener with just 6 of the calories of
table sugar. It doesnt raise blood sugar or
insulin levels, and has antioxidant
properties. So our tablets taste great and are
well tolerated in the body, and dont cause
tooth decay. Most of our customers have also
reported gaining better sleep and more energy,
with improvements in focus, memory and a boost
to their metabolism. Weve heard from some very
happy people with recurrent sprain and strain
injuries which have cleared up right after they
started taking NMN.
12
HOW OFTEN SHOULD I TAKE HALO1618 NMN?
FAQ
What we found is that its more important how
often you take NMN than how much you take. This
is because the product remains active in the
body for around 60 minutes, diminishing quickly
after that. So we created a tablet with a lower
dosage and put 180 of them into each bottle, to
enable you to deliver a constant supply of NMN to
your bloodstream. Taking a HALO1618 tablet once
every hour during the day gives your body a
constant supply of rejuvenating NMN. WHICH LAB
HAS THE HALO1618 NMN BEEN TESTED ? As well as
being batch-tested every time we manufacture NMN,
we have our raw material independently tested by
Health Level One in New York. Weve posted lab
results showing that our capsules contain real
NMN. Download here. WHY DO YOU USE
ERYTHRITOL? Erythritol is known as a sugar
alcohol. The name is misleading as it contains no
alcohol, but is commonly used as a sweetener in
many foods. Erythritol is 70 as sweet as sugar
but with only 6 of sugars calories. It is an
ideal catalyst for transporting NMN to the
bloodstream via sublingual delivery. Erythritol
is known to cause fewer digestive issues than
alternatives such as Xylitol, and does not raise
blood sugar or insulin levels or cause tooth
decay. Fun Fact Erythritol is also non-toxic
to dogs, which we love..
13
About Sinclair Laboratories

• The t eam at Si ncl ai r Labor at or i es has
  been wor ki ng t i r el essl y on br i ngi ng you
  t he wor l d s most ef f ect i ve NMN pr oduct
  . We r e f i r m bel i ever s i n t he heal i ng
  and age-r ever si ng capabi l i t i es of NMN,
  and we ve seen f ant ast i c
• i mpr ovement s i n our own l i ves f r om t aki
  ng t hi s suppl ement . We l ove hear i ng gr
  eat st or i es f r om our cust omer s about how
  our pr oduct has changed t hei r
• l i ves f or t he bet t er .
• Let s f ace i t , whoever needed a compel l i
  ng r eason t o f eel younger ? We spend a l ot
  of t i me and ef f or t r esear chi ng how t o
  make our pr oduct s bet t er i n ever y way. We
  r e ver y ex ci t ed about our HALO1 61 8 pr
  oduct , whi ch we ve t est ed
• f r om t he gr ound up, and we want you t o be
  happy wi t h i t t oo. We d l ove t o hear your
  f eedback on how we coul d make f ur t her i mpr
  ovement s.
• To know mor e about our pr oduct , Vi si t our
  Websi t e nmn. heal t h