Navya_Sharma

1
Factors Associated with Cord Blood IgE Levels

• The IgE is the short form of Immunoglobulin E
  which are antibiotics produced by the immune
  system.
• In case if a person has come in contact with any
  allergen and is suffering from allergy then
  Immunoglobulin E (lgE) antibodies are produced by
  our immune system to tackle the challenges.
• Further the role of these antibodies is to reach
  the targeted cells that are responsible for
  allergic reactions.

2
Factors Associated with Cord Blood IgE Levels

• The quantity of lgE antibodies is small in our
  blood but in case if these are found in higher
  quantity then that indicates that our body is
  overreacting to allergens.
• Allergic disorders be best predicted by checking
  the lgE levels in the cord blood of any child.
• Its yet not certain how the fetal
  characteristics of mother or father will affect
  the marker.

3
Factors Associated with Cord Blood IgE Levels

• The epidemiologic data suggests that there has
  been an increased prevalence of atopy in recent
  decades.
• Our tendency to cause allergic diseases in our
  body is what we call as Atopy.
• The gestational period is the time where the
  development of immune system and atopy
  predisposition is initiated.
• Mostly in the earlier phases of your life, atopic
  diseases will be cured.

4
Factors Associated with Cord Blood IgE Levels

• Due to fatal effects and the above-mentioned
  facts people are getting more aware about atopic
  disorders and studies are taking place on the
  methods for prevention of this disorder.
• Best treatment is only possible if disease is
  detected in early stage.
• Disease can be best cured only if you are able to
  recognize the symptoms in its early stage and
  disease is diagnosed.

5
Factors Associated with Cord Blood IgE Levels

• Normally in the 11th week of gestation period lgE
  starts to appear in cord blood which is secreted
  by fetus.
• According to experts the lgE levels in cord blood
  can become a deciding a factor in determining
  atopy diseases and can be best used to identify
  this disease in newborns.
• The lgE levels can hence prevent the high risk of
  this disease in initial phases.

6
Factors Associated with Cord Blood IgE Levels

• Though studies are going on to check how accurate
  is the prediction of atopy diseases from lgE
  levels.
• Doctors are trying their best to check the
  connection between lgE levels in umbilical cord
  blood and the various factors of atopic diseases.
• To serve the purpose there was a special research
  conducted in which 181 infants and their mothers
  were called for the research purpose.

7
Factors Associated with Cord Blood IgE Levels

• The data regarding the maternal history,
  demographic data, and medical history data to the
  pregnant women, after that the blood samples of
  the umbilical cord blood were collected for the
  study.
• Through this research the connection between lgE
  levels of cord blood and various maternal
  activities like delivery type, number of
  pregnancies, pregnancy related allergies were
  found.
• The lgE levels of mothers cord blood was also
  related to the infants cord blood.

8
Factors Associated with Cord Blood IgE Levels

• It was thus concluded that among the evaluated
  factors, the presence of any kind of allergic
  disorder in the mother or her family and elevated
  maternal blood IgE levels are associated with
  cord blood IgE of the child.
• Maternal age, delivery type, season of birth, etc
  are some other crucial predictors that can be
  used for the analysis of the IgE levels of the
  cord blood.