Recombinant Protein Market Analysis | CMI

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RECOMBINANT PROTEIN MARKET ANALYSIS

• Recombinant Protein Market, by Product Type
  (Hormones, Growth Factors, Cytokines, Plasma
  Protein Factor, Recombinant Metabolic Enzymes,
  Immune Checkpoint Regulators, and Others), By
  Application (Drug Discovery Development,
  Biopharmaceutical Production, Basic Research, and
  Others), By End User (Biopharmaceutical
  Companies, Academic Research Institutes,
  Contract Research Organizations, and Others), and
  Region - Global Industry insights, and Forecast
  till 2025
• The global recombinant protein market was valued
  at US 347.2 million in 2016 and is expected to
  witness a robust CAGR of 6.2 over the forecast
  period (20172025).

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Market Drivers

• Increasing research development expenditure on
  biologic drugs is expected to boost demand for
  recombinant proteins for research purposes
• Biopharmaceutical organizations are focusing on
  research and development of novel biosimilars for
  life threatening diseases such as cardiovascular
  diseases, cancer, metabolic disorders such as
  diabetes, and certain rare conditions such as
  hemophilia. According to Pharmaceutical Research
  and Manufacturers of America (PhRMA), 2016,
  member companies invested around US 58.8 billion
  in research and development in 2015, of which,
  majority was by all biopharmaceutical companies
  in the U.S. Rare disease medical space holds
  potential as there is relatively low competition.
  This is owing to less understanding of the
  disease progression pathways and entities.
  Therefore, companies could focus on RD for
  development of biologics and subsequently
  biosimilars in this space. Some of the
  biosimilars available in the market include
  Eprex, manufactured by Janssen-Cilag Pty Ltd.,
  which has been successful in treatment of anemia.
  Demand for biosimilars is increasing
  significantly, owing to high prices of biologics,
  in turn leading to high demand for recombinant
  protein.

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Figure 1. Global Recombinant Protein Market
Share, by Application () 2017 and 2025
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• Technological advancement in production of
  recombinant protein is expected to fuel growth of
  the Recombinant Protein Market
• Advancement in technologies in various areas
  associated with or facilitating recombinant
  protein production have supported growth of
  recombinant protein market. For instance,
  development of alternative expression
  technologies such as mammalian cell expression,
  baculovirus expression, and E.coli expression,
  development of alternative cell lines, and
  enhanced cell culture systems have simplified and
  optimized recombinant protein processes.
  Furthermore, advanced chromatography protein
  purification methods such as FPLC and HPLC help
  in providing highly purified clinical grade
  recombinant proteins. Clustered regularly
  interspaced short palindromic repeats (CRISPR)
  technique is a genome editing technique used to
  target destruction in human cells and can improve
  recombinant protein production. Moreover,
  advancements in bioreactor systems have improved
  the products output within shorter time.
  According to National Centre for Biotechnology
  Information (NCBI), in 2014, about 65.6 of
  clinical scale manufacturers and 42 of
  commercial manufacturers adopted single use
  bioreactor for improvement in their
  bioprocessing.

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Market Restraints

• Factors such as complex manufacturing process,
  high costs, and requirement of high quality of
  these products (responsible for high costs) are
  expected to hinder growth of the market over the
  forecast period.

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Key Players

• Some major players operating in the recombinant
  protein market include Crown Bioscience, Inc.,
  ProSpec Tany TechnoGene, Ltd., BPS Bioscience,
  Inc., Sigma Aldrich Company Ltd., Novoprotein
  Scientific, PeproTech, Inc., Feldan Bio, Inc.,
  BioVision, Inc., HumanZyme, Inc., and GenScript
  Biotech Corporation.

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