What are the Side Effects of Nintedanib?

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Brand OFEVGeneric NINTEDANIB

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• What is NINTEDANIB?
• Nintedanib is used in people with diseases that
  cause scar tissue (fibrosis) to form deep within
  the
• lungs. The scar tissue thickens and becomes
  stiff over time, which can make it harder for
  your lungs
• to work. Decreased lung function can make
  it hard for you to breathe. Other medical
  problems can
• occur when your brain, heart, and other
  organs do not get enough oxygen.
• Nintedanib is used to treat a lung disease called
  idiopathic pulmonary fibrosis (IPF).
• Nintedanib is also used to treat chronic (long
  lasting) interstitial lung disease in which the
  scar tissue keeps getting worse.
• Nintedanib is also used to slow the decline in
  lung function in people with a disorder called
  systemic sclerosis-associated interstitial lung
  disease (sometimes called scleroderma-associated
  ILD).
• Nintedanib is not a cure for IPF or ILD, but
  nintedanib can slow the effects of these diseases
  on your lungs.
• Nintedanib may also be used for purposes not
  listed in this medication guide.

Source https//www.drugs.com/mtm/nintedanib.html
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• How should I take NINTEDANIB?
• Your doctor will perform blood tests to make sure
  you do not have conditions that would prevent you
  from safely using nintedanib.
• Follow all directions on your prescription label
  and read all medication guides or instruction
  sheets. Your doctor may occasionally change your
  dose. Use the medicine exactly as directed.
• Take with food and a full glass of water.
• Swallow the capsule whole and do not crush, chew,
  break, or open it.
• Take your doses at regular intervals, usually
  every 12 hours.
• Nintedanib can cause severe diarrhea, which can
  be life-threatening if it leads to dehydration.
  You may need to take medication to prevent or
  quickly treat diarrhea.
• Your doctor may recommend you have an
  anti-diarrhea medicine such as loperamide
  (Imodium) available at all times while you are
  taking nintedanib. Take the anti-diarrhea
  medicine as directed on the label, or as
  prescribed by your doctor.
• Drink plenty of liquids and call your doctor at
  once if you have diarrhea while taking nintedanib.

Source https//www.drugs.com/mtm/nintedanib.html
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• What happens if I miss a dose?
• Skip the missed dose and use your next dose at
  the regular time. Do not use two doses at one
  time.
• What happens if I overdose?
• Seek emergency medical attention or call the
  Poison Help line at 1-800-222-1222.
• Do not take more than 300 milligrams of
  nintedanib in one day.
• What should I avoid while taking NINTEDANIB?
• Smoking can make nintedanib less effective. Avoid
  smoking while taking nintedanib, or try to quit
  before you start this treatment.
• Avoid taking an herbal supplement containing St.
  John's wort.

Source https//www.drugs.com/mtm/nintedanib.html
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• NINTEDANIB
• Get emergency medical help if you have signs of
  an allergic reaction hives difficult breathing
  swelling of your face, lips, tongue, or throat.
• Call your doctor at once if you have
• severe ongoing nausea, vomiting, or diarrhea
• severe stomach pain, bloating, or tenderness
• bleeding from your rectum or blood in your
  stools
• easy bruising or bleeding, any wound that will
  not heal
• fever, chills, cough with mucus, chest pain,
  feeling short of breath
• heart attack symptoms--chest pain or pressure,
  pain spreading to your jaw or shoulder, nausea,
  sweating
• liver problems--stomach pain (upper right side),
  loss of appetite, tiredness, dark urine, jaundice
  (yellowing of the skin or eyes) or

Source https//www.drugs.com/mtm/nintedanib.html
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