Aesthetic Skin Whitening—The New Normal

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Aesthetic Skin WhiteningThe New Normal

• Efforts To Lighten The Skin Date Back To At Least
  The 1500s In Asia. Skin Whitening, Also
  Recognized As Skin Lightening And Skin Bleaching,
  Is The Exercise Of Using Chemical Substances In
  An Attempt To Lighten The Skin Or Provide An Even
  Skin Colour By Reducing The Melanin Concentration
  In The Skin. Several Chemicals Have Been Shown To
  Be Effective In Skin Whitening, While Some Have
  Proven To Be Toxic Or Have Questionable Safety
  Profiles. In Pakistan, Specifically, Over Half Of
  Skin Care Products Are Sold To Whiten Skin.
• But Searching For Skin Whitening Treatments One
  Must Understand The Difference Between A
  Generalized Body Whitening And A Target Whitening
  (Hyperpigmentation On Face Neck, Hands, Feet,
  Knuckles, Etc.). As Both Skin Whitening Treatment
  And Skin Pigmentation Treatment Are Both Poles
  Apart From Each Other. Mechanism Of Action And
  Pathology For Both Are Entirely Different.
• Before Moving Towards The Skin Whitening
  Treatments Lets Understand Why Generalized Skin
  Whitening Treatment Is Different From Targeted
  Skin Whitening Treatment.

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Hyperpigmentation

• Is A Disorder Of The Melanocytes Go Under
  Overdrive And Produce Excess Melanin Causing
  Patchy Irregularities And Darkened Patches On The
  Skin Especially Face, Neck Hands And Knuckles.
  There Are Many Causes Of Hyperpigmentation Which
  Also Include Sun Exposure, Vitamin And Iron
  Deficiencies, Hormonal Abnormalities To Name But
  A Few. Skin Hyperpigmentation Can Present As Age
  Spots, Melasma, Or Post-Inflammatory
  Hyperpigmentation. Pigmentation Of The Skin Is
  Determined By The Cells Called Melanocytes Which
  Produce The Pigment Melanin. Melanin Is Designed
  To Protect The Skin From The Harmful UV Rays Of
  The Sun.

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Skin Whitening

• On The Other Hand Is The Process In Which The
  Melanin Pigment In The Skin Is Reduced To Give A
  Whiter Complexion. Those With Dark Complexion
  Have More Melanin And The Quantity Of Melanin
  Determines The Colour Of A Persons Skin. Melanin
  Is Manufactured By Cells Called Melanocytes. The
  Melanin Quantity Of A Persons Skin Depends Upon
  The Genetic Build-Up. The Production Of Melanin
  Is Affected By Exposure To The Sun, The Degree Of
  Damaged Skin, And Exposure To Chemicals. In Skin

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Whitening Treatment

• The Melanin Is Reduced Which Ultimately Results
  In Whiter Complexion.

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Generalized Body Whitening

• Intravenous Drips
• Intravenous Therapy Drip Is A Treatment That Will
  Deliver The Fluids Directly Into A Vein. The
  Intravenous Route Of The Administration Is Used
  For The Injection Using A Syringe At A Higher
  Pressure. It Is The Same For The Infusion That Is
  Only Using The Pressure Supplied By Gravity, The
  Intravenous Infusion Will Be Referred As Drips.
  Generalized Body Whitening Through IV Drips Is An
  Effective Procedure As Vitamins, Minerals And
  Peptides Are Infused In The Blood That Improve
  The Skin Health And Give A Radiance From Within.
  Generalized Body Whitening Treatment Involves
  Detoxification Of Liver Resulting In A Cleansed
  Blood, So That You Achieve A Whiter Skin With A
  Natural Glow.
• Want Healthy, Glowing White Skin? If Yes, Then
  The IV Drip Therapy Can Help You To Solve Or
  Improve The Condition Through An Infusion Of
  Different Vitamins. The Treatment Gained
  Popularity In The Past Because It Will Provide
  You A Youthful And Radiant Glow Along With The
  Detoxification Of Liver.

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Targeted Skin Whitening

• Most Of The Patients Coming For Skin Whitening
  Prefer Targeted Skin Whitening On The Patchy
  Hyperpigmented Areas Commonly Face, Neck, Hands,
  Feet And Knuckles. Targeted Skin Whitening Is
  Done Through A Combination Of Treatments That
  Encompass Lasers, Peels, Mesotherapy And
  Inhibition Of Tyrosinase.

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Laser Skin Lightening

• A Laser Can Also Be Used To Lighten Blemishes Or
  Dark Patches Of Skin Especially On Face, Neck,
  Hands, Feet And Knuckles. This Works By Either
  Removing The Outer Layer Of Skin Or Damaging The
  Cells That Produce Melanin.
• Laser Skin Lightening May Work For Some People,
  While For Others It May Not Have Any Effect, Or
  The Skin Lightening May Only Be Temporary.
•  

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Transfer Of Melanosomes

• Within The Skin, Melanocytes Are Existing In The
  Basal Layer Of The Epidermis From These
  Melanocytes Originate Dendrites That
  Reach Keratinocytes.
• Melanosomes Along With The Melanin They Hold, Are
  Transferred From Melanocytes To Keratinocytes
  When Keratinocytes Are Low In The
  Epidermis. Keratinocytes Carry The Melanosomes
  With Them As They Move Towards The Surface.
  Keratinocytes Contribute To Skin Pigmentation By
  Holding The Melanin Originated In Melanocytes And
  Inducing Melanogenesis Through Chemical Signals
  Directed At Melanocytes. The Transfer Of
  Melanosomes To Keratinocytes Is A Necessary
  Condition For The Visible Pigmentation Of The
  Skin. Blocking This Transfer Is A Mechanism Of
  Action Of Some Skin Whitening Agents.
• The Protease-Activated Receptor 2 (PAR2) Is
  A Transmembrane And G-Protein Coupled Receptor
  Expressed In Keratinocytes And Involved In
  Melanocyte Transfer Antagonists Of PAR2 Inhibit
  The Transfer Of Melanosomes And Have Skin
  Whitening Affects, While Agonists Of PAR2 Have
  The Opposite Effect.

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INHIBITION OF TYROSINASE

• Upregulation Of Tyrosinase Caused By Tyrosinase
  Inhibitors. Numerous Skin Whitening Agents,
  Including Tyrosinase Inhibitors, Have Been Found
  To Cause An Increase In The Expression Of
  Tyrosinase, Which By Itself Would Increase
  Melanin Synthesis.
• Microphthalmia-Associated Transcription
  Factor (MITF) Is The Master Transcription
  Factor That Controls The Expression Of TYR, TRP1
  And TRP2, MART1, PMEL17, And Many Other Important
  Proteins Involved In The Function Of
  Melanocytes. Downregulation Of MITF Declines
  Melanogenesis And Is A Mechanism Of Action Of
  Some Skin Whitening Agents. Numerous Signalling
  Pathways And Genetic Mutations Impact The
  Expression Of MITF.

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DESTROYING MELANOCYTES

• Some Compounds Are Known To Destroy Melanocytes
  This Mechanism Of Action Is Often Used To Remove
  The Remaining Pigmentation In Cases Of Vitiligo.

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WHAT TO DO IF YOU HAVE PROBLEMS

• Cosmetic Procedures Can Sometimes Go Wrong And
  The Results May Not Be What You Expected.
• If You Have Laser Skin Lightening And Are Not
  Happy With The Results, Or Think The Procedure
  Was Not Done Properly, You Should Take Up The
  Matter With The Hospital Or Clinic Where You Were
  Treated. It Is Best That You Go Back To The
  Practitioner Who Treated You If You Have Any
  Complications.

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 Why London Aesthetics?

• Wondering Why London Aesthetics Rejuvenation
  Centre Is The Right Place For You To Visit? Our
  Experts Are Having Years Of Experience And They
  Will Be Using The Right Combinations Of Technique
  And Appropriate Equipment To Provide Satisfactory
  Results To The Customers.
• With The Extended Choices Of Diverse Skin
  Whitening Treatments At London Aesthetics And
  Rejuvenation Center, It Has Become Very
  Convenient Than Before To Re-Establish The Lost
  Skin Glow And Skin Tone. 
• If You're In Search Of Best Skin Whitening
  Treatment, At An Evaluated Cost, And A Range Of
  Types To Choose From, Etc. Then Our Centers In
  Lahore And Faisalabad Are The Best Places For
  You.