What are the side effects of bendamustine?

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Brand TREANDA Generic BENDAMUSTINE

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• What is BENDAMUSTINE?
• Bendamustine is used to treat chronic lymphocytic
  leukemia. Bendamustine is also used to treat
  indolent B-cell non-Hodgkin lymphoma after other
  medicines have been tried without successful
  treatment of this condition.
• Bendamustine may also be used for purposes not
  listed in this medication guide.
• Warnings
• Tell your caregivers right away if you have any
  type of skin rash after being treated with
  bendamustine.
• Before taking this medicine
• You should not be treated with bendamustine if
  you are allergic to bendamustine, polyethylene
  glycol, propylene glycol, or mannitol (Osmitrol).
• Tell your doctor if you have ever had
• a weak immune system
• fever or other signs of infection.

Source https//www.drugs.com/mtm/bendamustine.ht
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• How is BENDAMUSTINE given?
• Bendamustine is given as an infusion into a vein.
  A healthcare provider will give you this
  injection.
• Bendamustine is usually given for 2 days in a row
  every 21 to 28 days. Your doctor will determine
  how long to treat you with this medicine.
• You may be given other medications to help
  prevent certain side effects of bendamustine.
• Tell your caregivers if you feel any burning,
  pain, or swelling around the IV needle when the
  medicine is injected.
• Bendamustine affects your immune system. You may
  get infections more easily, even serious or fatal
  infections. Your doctor will need to examine you
  on a regular basis.
• If you've ever had hepatitis B, using
  bendamustine can cause this virus to become
  active or get worse. You may need frequent liver
  function tests while using this medicine and for
  several months after you stop.

Source https//www.drugs.com/mtm/bendamustine.ht
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What happens if I miss a dose? Call your doctor
for instructions if you miss an appointment for
your bendamustine injection. What happens if I
overdose? Seek emergency medical attention or
call the Poison Help line at 1-800-222-1222. What
should I avoid while receiving
BENDAMUSTINE? Avoid driving or hazardous
activity until you know how bendamustine will
affect you. Your reactions could be impaired.
Source https//www.drugs.com/mtm/bendamustine.ht
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• Bendamustine
• Get emergency medical help if you have signs of
  an allergic reaction (hives, difficult breathing,
  swelling in your face or throat) or a severe skin
  reaction (fever, sore throat, burning in your
  eyes, skin pain, red or purple skin rash that
  spreads and causes blistering and peeling).
• Seek medical treatment if you have a serious drug
  reaction that can affect many parts of your body.
  Symptoms may include skin rash, fever, swollen
  glands, muscle aches, severe weakness, unusual
  bruising, or yellowing of your skin or eyes.
• Call your doctor at once if you have
• fever, chills, or itching during or shortly after
  the injection
• pain, swelling, redness, skin changes, or signs
  of infection where the medicine was injected
• severe ongoing nausea, vomiting, or diarrhea
• liver problems--right-sided upper stomach pain,
  vomiting, loss of appetite, yellowing of your
  skin or eyes, and not feeling well
• low blood cell counts--fever, chills, tiredness,
  mouth sores, skin sores, easy bruising, unusual
• bleeding, pale skin, cold hands and feet,
  feeling light-headed or short of breath.

Source https//www.drugs.com/mtm/bendamustine.ht
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