Import Zelboraf Vemurafenib in India (1)

1
How Vemurafenib (Zelboraf) is used for cancer
treatment?
The targeted therapy is the cancer treatment that
focuses on specific molecules within the cancer
cells. The drug works by blocking the abnormal
molecules' functionality to slow the growth and
spread of cancer, like melanoma.
2
Import Zelboraf Vemurafenib in India
The systemic cancer treatments include the
targeted therapy, and it reaches the part of the
human body through the bloodstream. These drugs
fight the cancer cells which have spread or
metastasized from the original tumor to other
areas. Vemurafenib is the drug that shrinks the
tumors and helps patients with advanced melanoma
live longer. To import Zelboraf Vemurafenib in
India, the patient needs to show the prescription
to a specialist druggist.
3
What is the Vermurafenib?

• Vemurafenib is the BRAF is an inhibitor that
  works
• It is the type of targeted therapy that is the
  signal transduction inhibitor.
• It helps to stop or slow the growth and spread of
  melanoma cells.

4
How does the drug work?
Vemurafenib blocks the mutated protein activity
known as the BRAF, the molecule which helps to
regulate the growth of the cells. The BRAF
mutation signals the cells to develop abnormally
and divides out of control. These cells grow into
melanoma tumors. About half of all melanomas do
have the BRAF mutation in them. The medication is
specifically targeted at the V600E mutated BRAF
protein. The drug interferes with the abnormal
with BRAF signals to stop or slow the
out-of-control cell growths.
5
Who benefited from Vermurafenib?

• The U.S Food and Drug Administration (FDA) has
  approved Vemurafenib in 2011 to treat patients in
  the advanced stages of melanoma
• Stage III is unresectable that is unable to be
  completely removed by the surgery.
• Stage IV is also known as metastatic melanoma
  cells, which have spread to the organs and the
  other parts of the body.
• Vemurafenib works only in the patients who have
  positive for the BRAF V600E mutation. If the
  patients have melanoma, the physicians would have
  the melanoma tested for the mutation before
  prescribing Zelboraf. The physician would send
  the sample for biopsy. Depending on the biopsy
  report, they may ask experts to import Zelboraf
  Vemurafenib in India.

6
How is the Vemurafenib given?

• Patients taking Vemurafenib are given orally.
• The recommended dosage of the medicine is twice a
  day.
• Depending on how the patients respond to the
  treatment, the doctor might adjust the patient's
  dose.
• The patients will usually continue to take
  Vemurafenib until their melanoma is worsened or
  experience the unaccepted side effects.

7
What are the goals of vemurafenib?

• Vemurafenib works as the targeted melanoma cells
  with the goals like
• It slows the growth or the spread of melanoma
• It shrinks the melanoma tumors
• It helps the patients live longer.
• The large phase iii clinical trial results showed
  Vemurafenib improves the patients to outcomes
  more than DTIC (Dacarbazine), the chemotherapy
  drug.
• Melanoma treatments of Vemurafenib have side
  effects that are sometimes serious. The patients
  may talk to the doctors to learn more about the
  side effects of Vemurafenib and other melanoma
  treatment options.

8
How Vemurafenib (Zelboraf) is used for cancer
treatment?
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