In Vitro Toxicity Testing

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Contract Research Organizations Offering In
Vitro Toxicity Testing
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• Toxicity testing is an essential activity for
  many organizations developing new products
  designed to be sold into consumer markets.
• Pharmaceutical, chemical, cosmetic, food
  additive, and medical device companies are just a
  few organizations that run extensive toxicity
  testing programs to ensure their products are
  safe for the general public.

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• Companies operating toxicity testing programs
  often run in vivo studies (animal testing) and in
  vitro studies (cell or tissue-based testing).
• Because of increasing pressure from global
  regulatory organizations, negative press
  associated with animal studies, and the
  relatively low cost of in vitro models over
  traditional animal models, more and more
  companies are adding in vitro toxicity testing to
  their new product discovery pipeline.
• Due to the increasing demand for in
  vitro toxicity testing research services, a large
  number of new contract research organizations
  (CROs) have appeared over the last five to ten
  years offering in vitro testing services.

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1.
Iontox
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• IONTOX is a biotechnology company established in
  2014. IONTOX provides a number of in vitro
  toxicology services and also has a
  propeariatry in vitro integrated organ model.
  IONTOX serves a global client base in the
  pharmaceutical, cosmetic, chemical, tobacco,
  medical device, and food additive industries.
  Through the companys founder James McKim, Ph.D.,
  D.A.B.T.
• IONTOX has a connection to one of the first CROs
  exclusively offering in vitro toxicity testing as
  a service, CeeTox, which was also founded by Dr.
  McKim in the early 2000s.

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2. Covance

• Covance is one of the worlds largest CROs. They
  provide a number of contract research services to
  the drug, medical device, crop protection, and
  chemical industries.
• The company was incorporated in 1996 and
  headquartered in New Jersey. Worldwide the
  company has over 65,000 employees and provides a
  number of in vitro assessments.

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3. Eurofins

• Founded in 1987, Eurofins provides testing and
  support services to the pharmaceutical, food,
  environmental, and consumer products industries.
  They provide a number of cellular assay services,
  in vitro pharmacology profiling, and
  ADME-toxicity.
• Eurofins has a large network of over 900
  independent companies in over 50 countries and is
  committed to providing quality science.

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4. Charles River

• Charles River Laboratories inc. is a contract
  research organization providing numerous
  preclinical and clinical laboratory services for
  drug discovery. Charles River Laboratories was
  founded in 1947 and has since grown to be another
  one of the largest CROs supporting the
  pharmaceutical industry.
• In recent years Charles River has made a number
  of acquisitions and offers a wide array of in
  vitro assays for toxicity testing.

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Thanks!