All about High Shear Mixer Granulator

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All About High Shear Mixer Granulator
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Need of High Shear Mixer Granulator

• Used to mix the ingredients for granule
  preparation before compression.
• Has controlled effective channelized process.
• Helps to achieve product homogeneity fluidity.
• Provides stability with mechanism of lower heat
  transfer.
• Ensures clean hygienic air medium using proven
• manufacturing expertise.

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Important Parts of Rapid Mixer Granulator

• A cylindrical or a conical cylindrical mixing
  drum
• An impeller with a trio blade system
• A primary chopper and a supplementary chopper
• Motor and a discharge pot

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Advantages of High Shear Mixer Granulator

• Granulation machine offers a lot of advantages
  such as
• Need small quantity of binder solution for
  granulation process.
• Helps in prediction of granulation endpoint.
• Reproducible less friable granules with uniform
  particle size
• distribution.
• Minimizes any exposure of drug dust to workers.
• Greater densification and production of less
  friable granules.

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Factors Affecting Granulation Process of High
Shear Granulator

• Physical properties of the material to be
  granulated
• Type quantity of the excipients used
• Type amount of binder solution used in the
  process
• Various process variables include
• Load of granulator bowl
• Impeller speed
• Granular design
• Wet massing tire

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Industries Using Rapid Mixer Granulators

• Pharmaceuticals
• Chemicals
• Cosmetics
• Food beverage
• General mixing industries

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Why Shree Bhagwati Pharma?

• Shree Bhagwati Pharma is involved in offering
  pharmaceutical
• project consultancies for turn key projects
  that are in line with
• international standards such as the WHO
  GMP, USFDA, MHRA,
• TGA and cGMP rules andregulations.
• These leads to flexibility and cost
  effectiveness, while at the
• same time meeting the required regulatory
  requirements.

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