CRISPR Technology Course

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About CRISPR Technology Course

• This course provides you with an insight into
  the fundamental principles of gene-editing and
  how CRISPR functions as a gene-editing tool.
  During the eight weeks, you'll be introduced to
  the significant ways in which CRISPR could be
  applied to healthcare, agriculture, food, and
  energy industries.
• CRISPR-Cas9 is a unique technology that enables
  geneticists and medical researchers to edit parts
  of the genome? by removing, adding or altering
  sections of the DNA? sequence. It is currently
  the simplest, most versatile and precise method
  of genetic manipulation and is therefore causing
  a buzz in the science world.

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How does the CRISPR Technology work?

• The CRISPR-Cas9 system works similarly in the
  lab. Researchers create a small piece of RNA with
  a short "guide" sequence that attaches (binds) to
  a specific target sequence of DNA in a genome.
  The RNA also binds to the Cas9 enzyme. As in
  bacteria, the modified RNA is used to recognize
  the DNA sequence, and the Cas9 enzyme cuts the
  DNA at the targeted location. Although Cas9 is
  the enzyme that is used most often, other enzymes
  (for example Cpf1) can also be used. Once the DNA
  is cut, researchers use the cell's own DNA repair
  machinery to add or delete pieces of genetic
  material, or to make changes to the DNA by
  replacing an existing segment with a customized
  DNA sequence.

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Scope of CRISPR Technology

• In cancer biology, the CRISPR-Cas9 device has
  a bright future ahead of it,9, because it is a
  technology that is adaptable, simple, convenient
  and efficient. The method introduces a novel
  approach to cancer treatment by allowing for
  modifications to the genome of target cells,
  which was previously difficult to achieve.
  Tessera Therapeutics' new technology could write
  therapeutic messages into genomes, treating
  genetic diseases at their source. CRISPR
  technology, a gene editing tool that can be used
  to splice and alter the DNA inside a cell, has
  for years been hailed as the future of genetic
  disease medicine.

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