Amyloidosis: Causes, Symptoms, Treatment & Diagnosis

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Amyloidosis Causes, Symptoms, Treatment
Diagnosis

• - Specialty Care Clinics

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Amyloidosis A Rare Disease

• Protein is the building block of the human body.
  But when protein gets built up in our tissues and
  organs leads to severe pain. The abnormal
  deposition of protein is clinically referred to
  as amyloidosis. The abnormal protein or amyloid
  fibrils get to build up in your tissues and
  organs leading to life-threatening organ failure.
  Amyloidosis affects the shape and functionality
  of the affected organs as well as tissues.
• Amyloid normally is not found in the body but is
  formed from various types of protein. Various
  organs may be affected such as the heart,
  kidneys, liver, spleen, nervous system, and
  digestive tract. A few varieties of amyloidosis
  occur in association with other diseases that can
  improve as the doctors treat the underlying
  disease.
• Although, amyloidosis is not a type of cancer it
  may be linked with certain blood cancers like
  multiple myeloma. Sometimes, its treatment may
  include chemotherapy that is similar to that used
  to combat cancer.

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What is the Cause of Amyloidosis?

• Amyloidosis can be caused by different factors
  including hereditary factors. Others can be
  caused by outside factors, such as inflammatory
  diseases or long-term dialysis. Many types of
  amyloidosis affect only a single organ or tissue
  in the body but in severe cases, it can even lead
  to multiple organ failures.
• Different types of amyloidosis include
• AL amyloidosis or immunoglobulin light chain
  amyloidosis This is also known as primary
  amyloidosis that is most common in developed
  countries. The organs affected under primary
  amyloidosis are the heart, kidneys, liver, and
  nerves.
• AA amyloidosis This is the secondary amyloidosis
  that is usually triggered by an inflammatory
  disease, such as rheumatoid arthritis, and
  affects mainly the kidneys, liver, and spleen.
  Advanced treatments of severe inflammatory
  conditions have resulted in a sharp decline in
  the number of cases of AA amyloidosis in
  developed countries.

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Signs and symptoms of amyloidosis

• Signs and symptoms of amyloidosis may include
• Joints Pain.
• Change in skin color.
• Numbness, tingling or pain in your hands or feet,
• Pain in your wrist along with carpal tunnel
  syndrome.
• Swelling of your ankles and legs.
• Swelling of the tongue.
• Severe fatigue and weakness.
• Shortness of breath even with minimal exertion.
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