Immunology Medicine-XELJANZ(tofacitinib) by Alleviare India

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ALLEVIARE LIFE SCIENCES PVT. LIMITED
It's a pharmaceutical distribution and marketing
company based in Delhi (INDIA) having operations,
Pan India. We are also a service providing
company for patients, doctors, hospitals and
government hospitals. Alleviare help in finding
sources and assisting with documentation work
for procuring medicines under, Named Patient
Program/Managed Access Program/Early Access
Program.
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About XELJANZ(Tofacitinib)

• XELJANZ (Tofacitinib) is the active ingredient of
  Xeljanz, is an immunosuppressant that blocks the
  action of Janus kinases,
• enzymes that play a crucial role in the process
  of inflammation and damage of the joints.
• Tofacitinib, by blocking the enzymes, reduces the
  inflammation and other symptoms of rheumatoid
  arthritis.

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XELJANZ is a prescription medicine called a Janus
kinase (JAK) inhibitor.
Indication Usage
XELJANZ is used to treat adults with moderately
to severely active rheumatoid arthritis in which
methotrexate did not work well. It is not known
if XELJANZ is safe and effective in people with
Hepatitis B or C. XELJANZ is not for people with
severe liver problems. It is not known if XELJANZ
is safe and effective in children.
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Most common side effects of Xeljanz
NoteThese are not all the
possible side effects of Xeljanz. For more
information, ask your doctor or pharmacist.
Skin rash Shingles Increased blood pressure
Abnormal blood tests Headache Diarrhea, Cold
symptoms -(Stuffy nose, sneezing, sore throat)
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DOSAGE AND ADMINISTRATION

1. XELJANZ XR (tofacitinib extended-release tablets)
   is not interchangeable or substitutable with
   XELJANZ Oral Solution.
2. Changes between XELJANZ and XELJANZ XR should be
   made by the healthcare provider see DOSAGE AND
   ADMINISTRATION.
3. Do not initiate XELJANZ/XELJANZ XR/XELJANZ Oral
   Solution in patients with an absolute lymphocyte
   count less than 500 cells/mm³, an absolute
   neutrophil count (ANC) less than 1000 cells/mm³
   or who have hemoglobin levels less than 9 g/dL.
4. Dose interruption is recommended for management
   of lymphopenia, neutropenia, and anemia see
   WARNINGS AND PRECAUTIONS, ADVERSE REACTIONS.
5. Interrupt use of XELJANZ/XELJANZ XR/XELJANZ Oral
   Solution if a patient develops a serious
   infection until the infection is controlled see
   WARNINGS AND PRECAUTIONS.
6. Take XELJANZ/XELJANZ XR/XELJANZ Oral Solution
   with or without food see CLINICAL
   PHARMACOLOGY.
7. Swallow XELJANZ XR tablets whole and intact. Do
   not crush, split, or chew.

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Alleviare Life Sciences Pvt. Ltd. S-1/5 First
Floor, Uphaar Cinema Complex Market, Green Park
Extn., South Delhi, New Delhi- 110016
kamal_at_alleviarelife.com Call Us 91-9818274099