The Best Granulation Equipment Manufacturer - Fve Healthcare

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We'vegot you www.fve.international
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Our Mission
We are accomplishing that by building indigenous
manufacturing capability and sharing technology
across the globe
Our purpose is deeply rooted in the belief that
all lives have equal value.
We Are Committed To Saving Lives.
Thus ensuring ACCESS to AFFORDABLE Life Saving
Drugs to everyone
We have over 700 manufacturing installations in
53 countries.
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Our consortium manufactures 
safe
safe
Clean Room Equipment Panels
Containment Systems (Isolators)
Water Generation System
1997
2005
2016
Granulation Equipment
Capsule Filling Machines
2012
2015
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OSD Formulation Process Flow
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OSD Formulation Solutions
Sieving
Blending
Coating
Milling
Compression
Granulation
Drying

1. Vibro Sifter
2. Turbo Sifter

1. Fluid Bed Dryer
2. Vacuum Tray Dryer

1. Multi Mill
2. Co Mill

1. Bin Blender
2. Octagonal Blender
3. Double Cone Blender
4. V blender

1. Tablet Compression Machine
2. Capsule filling Machine

1. Rapid Mixer Granulator
2. Fluid Bed Processor

1. Fluid Bed Coater
2. Auto Coater

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Oral Solid Dosage Process Equipment
(Granulation/Tablet line)
Vibro Sifter

• Features
• cGMP Model
• Stainless Steel Construction
• Multi Deck Unit
• Works on gyro principle.
• Gyratory motion is obtained from specially
  designed gyro motor which is fitted underneath
  the vibrating assembly.
• Vibrating assembly is isolated from the base by
  means of specially designed springs.
• Benefits
• Less Power Consumption
• Easy to dismantle for Cleaning Screen
• Noiseless Operation
• Dust Free Arrangement

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Turbo Sifter

• Features
• Works through vacuum transfer system
• Carrier between FBD/FBP and Co-mill.
• Benefits
• Easy to assemble, operate clean.
• Dust Free Operation
• Continuous Operation
• Cycle time reduction

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Rapid Mixer Granulator

• Features Uniform Granules by Gentle
  Processing Uniform Mixing And Granulation
  Fully Automatic Operation Based On PLC Control
  Better Productivity And Lesser Mixing Time Less
  Handling, More Hygienic Bowl Shape Design To
  Have No Dead Spaces
• Benefits
• Unique Impeller design reduces the process time
  while ensuring homogenous mixing and formation of
  uniform granules
• Unique Chopper design ensures effective
  reduction of oversized agglomerates, distribution
  of binder fluids and ideal compaction of
  granules.
• Unique Discharge Port design which ensures
  emptying of the granules from the main bowl in
  shortest time.

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Fluid Bed Dryer

• Features
• cGMP Model
• Stainless Steel Construction
• Three Stage Filtration
• Precise Temperature Control
• PLC controlled Operation
• Explosion Relief Flap
• Minimum Change Overtime
• Intelligent process control safety interlocks
• Benefits
• Reduced change over time
• Specially designed for minimum drying time.
• 100 Discharge

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Fluid Bed Processor

• Features
• PLC operations through recipe with 21 CFR
  compliance (as option).
• Three Stage Filtration i.e Pre-Filtration, Fine
  Filtration HEPA Filtration.
• Spray gun in the machine designed for precise
  control of the coating process.
• Spray nozzle in Single / Multi nozzle
  configuration.
• Provision of peristaltic pump for delivering
  spray medium through the nozzle.
• Sampling port is provided to take out sample of
  the material during process for testing without
  interrupting process cycle.
• Special design Temperature port is provided to
  monitor maintain accurate temperature through
  out process cycle.
• Fully sealed pneumatically controlled damper with
  0 100 positioning for accurate air
  monitoring and control.
• Benefits
• Reduced investment and downtime.
• Reduced process time due to unique bowl design.
  
• Easy for cleaning through CIP.
• Easy and quick change over.
• Safe operation.

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Fluid Bed Coater

• Features
• PLC operations through recipe with 21 CFR
  compliance (as option).
• Three Stage Filtration i.e Pre-Filtration, Fine
  Filtration HEPA Filtration.
• Spray gun in the machine designed for precise
  control of the coating process.
• Spray nozzle in Single / Multi nozzle
  configuration.
• Provision of peristaltic pump for delivering
  spray medium through the nozzle.
• Sampling port is provided to take out sample
  during process without interrupting the cycle.
• Temperature port is provided to monitor through
  out process cycle.
• Fully sealed pneumatically controlled damper with
  0 100 positioning .
• Benefits
• Reduced investment and downtime.
• Reduced process time due to unique bowl design.
  
• Easy for cleaning through CIP.
• Easy and quick change over.
• Safe operation.

TANGENTIAL
WURSTER
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Dry Co Mill with VTS

• Features
• VTS applied to carry the dried material from FBP
  bowl to co-mill, through Vertex flow pattern by
  means of rotating impeller, where the product
  travels by continuous centrifugal acceleration.
• 21 CFR Part 11 compliance.
• PLC operation through recipe as set by the user.
• Benefits
• Accurate Speed control.
• Continuous process.
• Easy for cleaning.
• Less change over time.

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Multi Mill

• Features
• Portable machine on castor wheels.
• Built in Variable Frequency Drive for multiple
  speeds.
• Multiple combination of Screens / Speeds / Number
  of Blades available.
• Direction of the Blade rotation can be changed
  using a Reversing switch for Hammer or Knife
  operation.
• Benefits
• Specially designed for high speed Granulating,
  Pulverizing.
• Utilizes the principle of variable force swing
  hammer blades having both knife and impact edges
  rotating with a selected screen to control
  particle size reduction.
• Streamlined flow path of material in vertical
  rotor machine.

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Blending Solutions

• Working Principle
• F brings you various blending technologies to
  help you choose blenders from Laboratory to
  Production capacities.
• Double Cone Blenders
• Octagonal Blenders
• Conta Blender
• V- Blender

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Bin Blender

• Bin blenders are the most widely used blenders
  owing to the flexibility it offers with
  different capacities, closed loop material
  transfer and better Mixing Efficiency. It also
  offers improved material handling both upstream
  and downstream.
• Features
• PLC operations through recipe as set by the user.
• Tumbling.
• Rotation in a diagonally eccentric plane.
• Benefits
• Operator friendly
• 360o Rotation
• Easy to install, dismantle clean.

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Octagonal Blender

• Features
• PLC operations through recipe as set by the user.
• 21 CFR Part 11 compliance.
• Material handling through Bin charging or a
  Vacuum charging system.
• Pneumatically actuated valves for dust free
  transfers
• Benefits
• Process large volume of material.
• Low Power Consumption.
• Bin charging system ensures Dust free closed
  system for Charging and Discharging of Product

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Double Cone Blender

• Features
• Suitable for dry blending of free flowing solids.
  
• Materials being blended are constantly being
  intermixed as the Double Cone rotates.
• Depending on the characteristic of the product,
  paddle type baffles can be provided on the shaft
  for better mixing, uniform blending and
  de-agglomeration
• Benefits
• Better mixing and Easy discharge
• Specially designed Cone which protects the gear
  box and motor from over loading.

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V-Blender

• Features
• Specially designed shape of the blender body
  results in a near complete discharge of product
  material.
• Provision of Internal attachments like lump
  breakers possible.
• VFD for variable speed.
• Benefits
• Simple design requiring minimum maintenance.
• Quick loading / unloading.
• Easy to clean.
• The Bin charging system can also be incorporated
  in it which provides dust free environment for
  charging and discharging.

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Tablet Compression Machine
FVE NX4

• Double sided rotary tablet press
• 10 ton main compression and 10 ton pre
  compression
• Turret with Interchangeable Facility Two piece
  turret with ELNP coating
• Motorized weight and thickness control adjustment
• Three paddle force feeding system
• Powder level sensor
• PLC control with TOUCH SCREEN IPPC ALONGWITH
  PRINTING FACILITY
• Auto lubrication system and drip feed lubrication
  for punches
• Auto weight control (AWC) single tablet
  rejection(AFR)
• ACVFD for main and force feeder motor

FVE II SE

• Double sided rotary tablet press
• 10 ton main compression
• Turret with HELICAL RING AND PINION DRIVE with
  WORM REDUCTION GEAR BOX
• Two piece turret with ELNP coating
• Manual side control for weight and thickness
  adjustment
• Two paddle force feeding system
• PLC control with TOUCH SCREEN HMI ALONGWITH
  PRINTING FACILITY
• Auto lubrication system and drip feed lubrication
  for punches Manual Hydraulic Pump

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Tablet Compression Machine
EFSP (For Effervescent Tablets)

• Single sided rotary tablet press
• 10 ton main compression
• Turret with WORM AND WORM RING DRIVESYSTEM
• Two piece turret with ELNP coating
• Manual control for weight and thickness
  adjustment inside cabinet
• Gravity feed frame
• Machine with VARIABLE PULLEY FOR TURRETSPEED
  CHANGE

FVE Minitabs

• Double layer rotary tablet press
• 10ton first layer pre compression and 10 ton
  final tablet main compression
• Turret with CENTRE DRIVE
• Two piece turret with ELNP coating
• Manual side control for weight and thickness of
  1stand 2nd laver
• Two paddle force feeding system and gravity feed
  frame
• Single Side Machine Available with 4 ton Pre
  Compression 10 ton main Compression

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Tablet Compression Machine
FVE EFSP II

• Single sided rotary tablet press
• 16 ton main compression
• Turret with HELICAL WORM AND WORM RINGDRIVE
  SYSTEM WITH WORM GEAR BOX
• Two piece turret with ELNP coating
• Manual side control for weight and thickness
  adjustment
• Gravity feed frame
• Machine with INTERCHANGEABLE FIXEDPULLEY FOR
  TURRET SPEED CHANGE
• Machine operation through control panel with
  pushbuttons and rotary potentiometer
• Manual hand pump lubrication system and drip feed
  lubrication for punches
• Manual hydraulic pump

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TABLETING PUNCHES
single tip punch
Multi design Dies
Multi tip punches
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Auto Coater

• Features
• Stainless Steel Construction Automated
  process to maintain uniformity of coating.
  Precise Temperature Control PLC controlled
  Operation Minimum Change Overtime Intelligent
  process control safety interlocks Pan cabinet
  is absolutely air tight and ensures no pollution
  in production environment
• Benefits
• Minimum Operator Intervention.
• Quick Changeover.
• Easy to clean.
• Safety

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Material Handling Equipment
Intermediate Bulk Container
Lifting and Positioning Device
Lifting and Tilting Device
Multi-mill
Conta Blender
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Material Handling Equipment
Lifting and Positioning Device

• Features
• Hydraulic operated lifting arm.
• Closed column construction with floor ceiling
  fastening.
• Adjustable mount stop.
• Flameproof construction Optional.
• Benefits
• Ease of control.
• Automatic hydraulic control as position control.
• Good balancing of attachments.
• 360 degree rotation of mast column.

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Material Handling Equipment
Tipper

• Features
• All contact parts AISI 316 non contact parts
  AISI 304.
• Pneumatically operated ON/ OFF valve at bottom.
• Flameproof construction - optional
• Benefits
• Unloaded material with inline process with cone
  mill, granulator and IBC for dust free process.
• Fully automatic system, with hydraulic lifting
  and tilting arrangement for quick and easy
  handling.
• Less Operation time.

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Closed Loop Granulation

We also offer Closed loop wall mount Units for
Granulation for labs with space constraints.
Sifting Granulation Drying Milling Blending
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 Complete Capsule Filling Line
Combination Powder Pellet Tablet.
Micro tablets. Capsule
in Capsule. Liquid in Capsule.
Softgel in Capsule.
Complete Production Line
RD Model
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R D model for Capsule filling
Features Maximum output 1500 to 3000 capsules /
hour Suitable for RD Lab, Process Development
Lab, Small size production, trial / batch
production Capable of filling powder, tablets,
micro-tablets, pellets and liquid under any
conditions Auto rejection of capsules Quick
Changeover No special tools required for
changeover Machine manufactured as per cGMP
norms Inbuilt vacuum pump for capsule
separation Optional Features Tablet attachment
with NFD (Non Filling Detection) Liquid Filling
Attachment Extra change part for capsule size
Tablet filling attachment Partial filling
attachment Dosing Disc IQ, 0Q, DQ
documentation provided on requirement
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Types of Capsule Filling machines
Fully automatic Capsule filling machine 25,000
200,000 capsules /hr
Semi-Automatic Capsule filling machine
20,000-40,000 capsules/hr
Manual capsule filling Capacity 7500 capsules/hr
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Accessories
Metal detector
Capsule Sorter Elevator
Sample Checkweigher
Capsule Polisher
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Empty Capsule Sorter
Capsule De-Duster 
Automatic Capsule Loader - Vertical / Horizontal
Filled Mini Capsule Sorter
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OSD Isolator

• Combining our engineering expertise in
  Containment and Granulation Fabtech Brings you
  Contained Granulation for Manufacturing of
  Oncology , Cytotoxic drugs ,Hormones and other
  such critical formulations.
• Offers from Material loading to tablet coating /
  Capsule filling line meets O E L 5.
• Below image represents Isolator for O S D with
  PLC which operates through automation.

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Containment Process
Pass Box Sifting Granulation
Drying Milling Blending Pass Box
Compression Coating Discharge
?Isolated process ? AHU
? CIP ? PLC
? 21 CFR compliance
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A Vast 10,000 Sq. Ft Manufacturing Unit
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Manufacturing unit for Oral Solid Dosage Process
Equipment
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Manufacturing unit for Capsule production line
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Our Global Landscape
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Countries and Product Lines
700 Installations
Acquired The Trust, Support, And Assurance Of Our
Clients Across The Globe
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Clients Snapshot?
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Compliance, Certifications Governance
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You can reach us digitally
www.fve.international
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Weve got you Thank you