Recurrent Pregnancy

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Recurrent Pregnancy
Dr. Neha Gupta
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What is Recurrent Pregnancy loss?
If you can get pregnant but keep miscarrying, it
is called recurrent pregnancy loss. Recurrent
pregnancy loss is classically defined as the
occurrence of three or more consecutive pregnancy
losses. A pregnancy loss is defined as a
clinically-recognized pregnancy involuntarily
ending before 20 weeks.
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What Causes Recurrent Pregnancy Loss?
Most pregnancy losses result from chromosomal, or
genetic, abnormalities, and are random events.
The abnormality may come from the egg, the sperm,
or the early embryo. Approximately 12-15 of all
clinically recognized pregnancies end in
miscarriage. However, it is estimated that at
least 30-60 of all conceptions will end within
the first 12 weeks of gestation. Up to 50 of the
time, the woman doesnt even realize that she was
ever pregnant. The risk of miscarriage increases
with the number of previous pregnancy losses but
is typically less than 50.
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What Treatment is Available for Recurrent
Pregnancy Loss?
The treatment recommendations for patients with
recurrent pregnancy loss are based on the
underlying cause of recurrent pregnancy loss. No
matter what the results of the work-up are, the
chance for a successful future pregnancy. Individ
uals in whom a karyotypic (a chromosomal or
genetic) abnormality is found are often referred
for genetic counseling. There, a specialist can
discuss what the genetic abnormality is and the
likelihood of having a chromosomally normal or
abnormal pregnancy in the future.
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Tests are done for couples with Recurrent
Pregnancy Loss?
A physician will take a detailed medical,
surgical, family, and genetic history and perform
a physical examination. Testing that may be done
includes karyotype analysis of both partners. The
karyotype is the chromosomal, or genetic, makeup
of a person. The uterus (the womb) and the
uterine cavity (inside of the womb) will often be
evaluated. There are several ways to evaluate the
uterine cavity, including an ultrasound, saline
ultrasound, hysterosalpingogram X-ray, MRI
(magnetic resonance imaging), and/or hysteroscopy
(to look inside the uterus).
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