Regenerative Possibilities for Kidney Disease with Cell Therapy

1
Regenerative Possibilities for Kidney Disease
with Cell Therapy

• Stem Cell Therapy for End Stage Kidney Failure
  An Effective Hope for Patients

2

• Current Treatment Options and Challenges
• The two main treatment options for ESRD are
• 1. Dialysis It acts as an artificial kidney by
  filtering waste and excess fluid from your blood.
  Though dialysis helps you live longer, it
  involves several hassles and risks
• Requires hemodialysis 3 times a week, each
  session lasting 3-5 hours
• Restricts fluid intake and changes lifestyle
• May cause symptoms like low blood pressure,
  cramps, and itching
• Carries risk of infections
• 2. Kidney transplant Though a transplant can
  restore near-normal kidney function, it faces
  challenges due to
• Shortage of donor's kidneys

3

• Lifelong immunosuppressant drugs suppress the
  immune system leading to other health issues
• Risk of organ rejection
• How Stem Cells Can Help Treat End-Stage Kidney
  Failure
• Stem cell therapy aims to regenerate defective
  kidney cells through cell replacement and
  reducing inflammation. Several clinical trials
  show stem cells may
• Reduce inflammation Stem cells secrete
  anti-inflammatory and immune-modulating proteins
  that downregulate inflammation in kidneys which
  is one of the main reasons behind ESRD.
• Repair damaged glomeruli Studies show
  mesenchymal stem cells can differentiate into
  glomerular cells in kidneys, aiding the repair of
  damaged glomeruli.

4

• Improve renal functions Patients receiving stem
  cell therapy for ESRD report short-term
  improvement in their creatinine levels,
  proteinuria, and GFR(a measure of kidney
  function).
• The prolonged time between dialysis Patients may
  require less frequent dialysis sessions after
  stem cell therapy.
• While stem cell therapy cannot fully reverse
  kidney failure currently, its regenerative
  effects at the cellular level help patients cope
  better with the disease.

5

• R3 Stem Cell International Offers Effective Stem
  Cell Therapy for Kidney Failure in Pakistan
• r3stemcell Pakistan offers minimally invasive
  stem cell therapy for patients with end-stage
  kidney failure. Their protocol involves
• Umbilical cord stem cells Obtained from donated
  umbilical cord blood which is abundant in
  mesenchymal stem cells.
• Intravenous infusion Stem cells are infused
  directly into the patient's bloodstream which
  then home in on damaged kidneys.
• Repeated treatments Patients may require 2-3
  sessions, 1 month apart, for best results.
• Patients have reported improvements in kidney
  functions, reduced inflammation and fatigue, and
  less frequent dialysis sessions after treatments
  at r3stemcell Pakistan.

6

• So stem cell therapy shows promise as an
  effective, less invasive hope for patients with
  end-stage kidney failure to improve their quality
  of life.
• In summary, though current medical options like
  dialysis and kidney transplants save the lives of
  ESRD patients, they suffer from limitations. Stem
  cell therapy aims to rejuvenate damaged kidneys
  using the body's own healing cells, showing
  potential as a supplementary treatment to help
  ESRD patients cope better.