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Description
Building on the success of the previous editions,
the Textbook of Drug Design and Discovery, Fifth
Edition, has been thoroughly revised and updated
to provide a complete source of information on
all facets of drug design and discovery for
students of chemistry, pharmacy, pharmacology,
biochemistry, and medicine. The information is
presented in an up-to-date review form with an
underlying and fundamental focus on the
educational aspects.Beginning with an
introduction to drug design and discovery, the
first eight chapters cover molecular recognition,
ligand-based drug design, and biostructure-based
drug design. The authors also discuss drug-like
properties and decision making in medicinal
chemistry, chemical biology, natural products in
drug discovery, and in vivo imaging in drug
discovery.The middle six chapters provide an
overview of peptide and protein drug design,
prodrugs in drug design and development, and
enzyme inhibitors. The authors also go through
receptors (structure, function, and
pharmacology), ion channels (structure and
function), and neurotransmitter transporters
(structure, function, and drug binding).The follow
ing chapters address important neurotransmitter
systems, GABA and glutamic acid receptors and
transporter ligands, acetylcholine,
histamine, dopamine and serotonin, and opioid and
cannabinoid receptors. The book concludes with an
examination of neglected diseases, anticancer
agents, tyrosine kinase receptors, and
antibiotics.
3
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Description
Building on the success of the previous editions,
the Textbook of Drug Design and Discovery,
Fifth Edition, has been thoroughly revised and
updated to provide a complete source of
information on all facets of drug design and
discovery for students of chemistry, pharmacy,
pharmacology, biochemistry, and medicine. The
information is presented in an up-to-date review
form with an underlying and fundamental focus on
the educational aspects.Beginning with an
introduction to drug design and discovery, the
first eight chapters cover molecular recognition,
ligand-based drug design, and biostructure-based
drug design. The authors also discuss drug-like
properties and decision making in medicinal
chemistry, chemical biology, natural products in
drug discovery, and in vivo imaging in
drug discovery.The middle six chapters provide an
overview of peptide and protein drug design,
prodrugs in drug design and development, and
enzyme inhibitors. The authors also go through
receptors (structure, function, and
pharmacology), ion channels (structure and
function), and neurotransmitter
transporters (structure, function, and drug
binding).The following chapters address important
neurotransmitter systems, GABA and glutamic acid
receptors and transporter ligands, acetylcholine,
histamine, dopamine and serotonin, and opioid and
cannabinoid receptors. The book concludes with an
examination of neglected diseases, anticancer
agents, tyrosine kinase receptors, and
antibiotics.
6
(PDF) Textbook of Drug Design and Discovery 5th
Edition Free