Heritability - PowerPoint PPT Presentation

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Heritability

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Epistatic effects. Maternal effects ... Identical twins (MZ) have identical genotypes, so any differences between ... Slope of the line approximates ... – PowerPoint PPT presentation

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Title: Heritability


1
Heritability!
  • A measure of the degree to which phenotypic
    variation in a population is attributable to
    genetic variation among individuals

2
Types of Heritability
  • Broad-sense reflects all possible genetic
    contributions to a populations phenotypic
    variance.
  • Variation in alleles
  • Dominance variation
  • Epistatic effects
  • Maternal effects
  • Narrow-sense only takes into account the portion
    of phenotypic variance that is due to additive
    (allelic) variance.

3
How to Estimate Heritability
  • Twin Studies
  • Identical twins (MZ) have identical genotypes, so
    any differences between (especially those raised
    apart) should be due solely to the environment
  • Parent-Offspring Regression
  • Slope of the line approximates heritability of
    the trait when offspring values are regressed
    against the average trait in the parents
  • Statistical Models
  • Analysis of variance, ANOVA
  • Has to do with comparing means by splitting the
    overall observed variance into different parts

4
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