International Trends and Needs in Drug Abuse Research

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NIDA International Forum
International Trends and Needs in Drug Abuse
Research June 16-19, 2006 Scottsdale, Arizona,
USA
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NIDA Mission

• To lead the Nation in bringing the power of
  science to bear on drug abuse and addiction,
  through
• support and conduct of research across a broad
  range of disciplines
• ensuring rapid and effective dissemination and
  use of research results to improve prevention,
  treatment, and policy

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NIDA International Mission

• Take advantage of unique opportunities to
  advance scientific knowledge through research
• Address the global impact of addiction on public
  health through activities that build research
  capacity internationally
• Effectively disseminate and share the knowledge
  gained through NIDA-supported research to
  scientists, treatment providers, and policy
  makers around the world

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NIDA Research Is Multidisciplinary
Epidemiology
Treatment
Neuroscience
Behavioral Science
Risk and Resilience
Prevention
AIDS and Other Medical Consequences
Children and Adolescents
Health Disparities
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NIDA Studies a Wide Array of Drugs

• Marijuana
• Cocaine
• Amphetamines
• Heroin
• PCP
• LSD
• Nicotine

• Ecstasy
• GHB
• Ketamine
• Rohypnol
• Barbiturates
• Inhalants
• Anabolic Steroids

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NIDA Studies the Health and Social Consequences
of Drug Abuse

• HIV/AIDS
• Hepatitis B
• Hepatitis C
• Tuberculosis
• STDs

• Lost Productivity
• Increased Health Care Expenditures
• Accidents
• Crime
• Violence

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NIDA Budget
(in millions)
Year
2002
2003
2004
2005 2006
1,000
- 0.6
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NIDA Organization

• Division of Basic Neuroscience and Behavioral
  Research
• Division of Clinical Neuroscience and Behavioral
  Research
• Division of Epidemiology, Services and Prevention
  Research
• Division of Pharmacotherapies and Medical
  Consequences of Drug Abuse
• Intramural Research Program
• International Program
• AIDS Research Program
• Center for the Clinical Trials Network
• Special Populations Office

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Drug Abuse The Worldwide Situation

• Global Prevalence of Drug Use1
• 200 million people used drugs at least once in
  the past 12 months
• 5 percent of people aged 15-64
• Users are from every country

1UNODC 2005 World Drug Report
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Global Prevalence of Drug Use, by Drug1
1UNODC 2005 World Drug Report
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Global Demand for Treatment, 20031
1UNODC
Opiates Cannabis Cocaine-type Amphetamine-type
stimulants Others No data available
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Global Consequences of Drug Abuse1, 2, 3

• Individual health
• Mortality and morbidity
• BBVs
• Overdose
• Accidents, trauma
• Comorbidity

• Public safety
• Drug-related crimes
• Violence
• Commercial sex work
• Corruption
• Organized crime and terrorism

• Social welfare
• Unemployment
• Homelessness
• Family disruption
• Social instability

• Economy
• Loss of productivity
• Diminishes legal economic activities

1UNODC 2005 World Drug Report 2WHO/UNODC/UNAIDS
Position Paper on Substitution Maintenance
Therapy for Opioid Dependence 3ONDCPDrugStory.org
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Global HIV Epidemic, 1990-20051
1UNAIDS 2006 Report on the Global AIDS Epidemic
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Drug Abuse and HIV/AIDS

• HIV Infections Attributed to Injection Drug Use1
• Between 5 and 10 globally (IDU reported in 136
  countries)
• More than 70 in some countries in
• Asia
• Eastern Europe
• HIV Infections Attributed to Risky Sexual
  Behaviors Related to Drug Abuse
• Unknown but significant

1WHO/UNODC/UNAIDS Position Paper on Substitution
Maintenance Therapy for Opioid Dependence
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Shifting Routes of HIV Infection
137,000 61,000 29,000
18,000 of new infections
Source Thai Working Group on HIV/AIDS Projection
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NIDA International Mission

• Scientific Mission
• The NIDA International Program fosters
  research to take advantage of special or unique
  opportunities to advance scientific knowledge on
  drug abuse and addiction. Such special
  opportunities may include the use of unusual
  talent, resources, populations, or environmental
  conditions in other countries that are not
  readily available in the United States or that
  augment existing U.S. resources.

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NIDA International Mission

• Public Health Mission
• As the single largest supporter of drug abuse
  research in the world, NIDA has the opportunity
  and the responsibility to partner with other
  countries to provide increased research capacity
  and science-based information to address
  addiction and related health issues around the
  world.

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NIDA International Goals

• Encourage rigorous collaborative and
  peer-reviewed international research
• Promote an international cohort of scientists who
  are knowledgeable of NIDAs research and methods
• Provide professional development opportunities
  and technical consultation to the international
  drug abuse research community
• Disseminate NIDAs research findings to
  international scientists and organizations

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NIDA International Research Awards, Fiscal Year
2005

• gt 200 Projects operated in 48 nations during
  FY2005
• 25 countries with multiple international research
  awards include

• Argentina
• Australia
• Bulgaria
• Canada
• China
• France
• Germany
• Hungary

• Poland
• Russia
• South Africa
• Spain
• Sweden
• Thailand
• United Kingdom
• Vietnam

• India
• Israel
• Italy
• Mexico
• Netherlands
• New Zealand
• Nicaragua
• Norway
• Pakistan

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Partnerships With Other NIH Institutes

• John E. Fogarty International Center
• NIAAA
• NIAID
• NICHD
• NIMH
• Office of AIDS Research

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NIDA International Program Announcement

• International Research Collaboration on Drug
  Addiction PA-06-050
• Research must be conducted by U.S. investigators
  in collaboration with non-U.S investigators
• Take advantage of special opportunities that
  exist outside the united states
• Address NIDAs scientific priority areas
• New or continuing R01 with standard receipt dates
• Expires January 3, 2009

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Current International Program Initiatives

• Drug Abuse and HIV/AIDS International Research
  Lessons and Imperatives

Supplement to Drug and Alcohol Dependence Research
reports from 15 countries
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Current International Program Initiatives

• Internet-based Tools for Research/Training
• Publishing International Research, www.PARINT.org
• Web-based Research Tools
• Technological Solutions for Supporting
  International Research Partnerships
• Online Manual on Opioid Substitution
  Pharmacotherapies
• Distance Learning Activities (eg, Online degree
  programs)

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Current International Program Initiatives

• Latin America Initiative
• Improve/stimulate creation of regional networks
  to improve surveillance and research
• Support training on addiction for front line
  medical staff
• Expand NIDAs library of Spanish-language
  resources
• Provide training and access for secondary data
  analysis to provide information useful to policy
  makers

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Current International Program Initiatives

• U.S. Netherlands Binational Agreement

• Unique program of collaboration with Dutch
  Addiction Program
• 10 co-funded research teams
• Highly productive (to date - 10 Scientific
  Journal Articles, 2 Book Chapters, 15
  Presentations at Scientific Meetings)
• New round of projects planned for 2006

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International Program Research Articles in 2005

• 102 Articles by 33 Fellowship Alumni during 2005

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NIDA International Activities and Initiatives
2006 and Beyond

• Strategic (build research capacity)
• Cost effective (leverage existing resources)
• Collaborative (maximize benefits of effort)

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NIDA International Research Priorities

• Linkages between HIV/AIDS and drug abuse
• Adolescent tobacco use and prenatal tobacco
  exposure
• Methamphetamine
• Inhalant abuse
• Drugged driving

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NIDA International Research Priorities

• Strengthening and stimulating research networks
• Partnering/collaborating with other international
  funding organizations
• Distance learning/web-based research and research
  training

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NIDA International Program Updates

• www.international.drugabuse.gov
• Bimonthly E-Letter

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NIDA International ProgramTraining and Exchange
Opportunities
Research Exchanges
Fellowships
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WHO/NIDA/CPDD International Traveling Fellowships

• Young Investigators from Developing Countries
• Present research and participate in
• NIDA International Forum
• CPDD Annual Scientific Meeting
• 1-week research visit to a NIDA grantee
• Application Deadline January 15, 2007

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NIDA International Forum

• Plenary Sessions
• Workshops
• Poster Presentations
• Networking
• Travel Awards
• (Deadline February 1)
• Plan Ahead for Next Year June
  15-18, 2007, Quebec City, Canada

Growth of Forum Participation
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2006 NIDA International Forum

• International Trends and Needs in Drug Abuse
  Research
• June 16-19, 2006
• The Fairmont Scottsdale Princess Hotel
  Scottsdale, Arizona, USA

• Saturday
• NIDA International Update
• International Drug Control Issues and
  Implications
• Focus on Latin America
• 2006 Awards of Excellence
• Networking Lunch
• Concurrent Sessions
• Web-based Tools
• Latin American Networks
• UNODC TreatNet

• Friday
• Grant Review Workshop
• Welcome and Networking Session

• Sunday
• Poster Session
• Monday
• Evaluation and Planning

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• Steven W. Gust, Ph.D., Director
• ipdirector_at_nida.nih.gov
• Dale Weiss, Program Analyst
• dweiss_at_nida.nih.gov