Depression: APA Guidelines Executive Summary

1
Depression APA Guidelines Executive Summary

• First line for new episodes
• Lithium I or lamotrigine II
• In more severely ill patients, consider lithium
  plus antidepressant III
• Consider ECT if life-threatening inanition,
  suicidality, psychosis I
• Breakthrough episodes
• Optimize primary agent II
• Add lamotrigine I, bupropion II, or
  paroxetine II
• Alternatives another SSRI II, venlafaxine or
  MAO-I II

I Recommended with substantial clinical
confidence II Recommended with moderate
clinical confidence III May be recommended on
the basis of individual circumstances
American Psychiatric Association. Am J
Psychiatry. 2002159(suppl 4)1-50.