Turner Syndrome

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Turner Syndrome

• By K.C.

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History

• identified in 1928
• Dr. Henry H. Turner
• chromosomal mutation discovered in 1959

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Karyotype

• disorder found on 23rd chromosome pair
• one X chromosome is partly or completely missing
• 23rd chromosome pair controls sex hormones and
  without an X, those hormones are missing

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Causes

• causes of Turner Syndrome are unknown
• no relationship between Turner Syndrome and
• environment
• race
• geography
• socioeconomic status

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Major Symptoms/Effects

• affects only females
• stunted growth
• no puberty
• no sex hormones
• infertility

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Minor Symptoms/Effects

• learning disabilities
• hearing loss
• obesity
• heart, kidney, thyroid disorders
• low hairline
• shield-shaped chest
• webbing of skin on neck

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Diagnosis

• 1/3 within 6 weeks of birth
• 1/3 during childhood
• 1/3 when supposed to go through puberty
• occurs in about 1 in 2500 females (.04)
• 2 of fetuses carrying babies with Turner
  Syndrome are miscarries

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Treatment / Prognosis

• plastic surgery for physical abnormalities
• hormone estrogen for puberty
• growth hormone for height
• support groups for self-esteem
• normal life expectancy
• lead normal, independent, productive lives

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Sources

• http//www.findarticles.com/cf_dls/g2606/0005/2606
  000548/p1/article.jhtml
• http//www.findarticles.com/cf_dls/g2602/0014/2602
  001312/p1/article.jhtml
• http//www.aaa.dk/turner/engelsk/Turnen.htm