Introduction to DNA methylation and its impact on gene regulation

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Lecture Introduction to DNA methylation and its
impact on gene regulation
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• Lecture 1
• Language
• Webpage http//www.molgen.mpg.de/steinhof/vorle
  sung_ws0708
• Outline
• Basics, Literature
• Seminar Dates and Topics
• Questions?

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Lecture Introduction to DNA methylation and its
impact on gene regulation
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Outline
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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Outline
WHEN ? Lectures November Thursday
1000-1230 Seminar TBA Where? SR 331,
Ihnestr 63-73
... Any changes find on the webpage!
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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... Discuss Seminar Dates ... How many people?
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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Literature Field of research make sure its a
recent publication! Unless for historical reasons
I will try to use publication later 2005 1.
Books
Molecular Biology of the Cell Bruce
Alberts Alexander Johnson Peter Walter Julian
Lewis Martin Raf Keith Roberts Garland
Publishing Inc,US 5th Edition (31. Dez. 2007)
Lehninger Principles of Biochemistry David L.
Nelson Michael M. Cox Palgrave Macmillan 4.
Edition (21. Juni 2004)
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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1. Books
DNA Methylation. Basic Mechanisms Current
Topics in Microbiology Immunology 2005 Walter
Doerfler Petra Böhm
DNA Methylation. Development, Genetic Disease and
Cancer 310 Current Topics in Microbiology and
Immunology 2006 Walter Doerfler Petra Böhm
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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1. Books
DNA Methylation, Epigenetics and
Metastasis Cancer Metastasis - Biology and
Treatment Springer 2005 M. Esteller
Epigenetics Cold Spring Habor Laboratory
Press 2007 C. David Allis Thomas Jenuwein Danny
Reinberg
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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1. Books
From Epigenesis to Epigenetics The Genome in
Context (Annals of the New York Academy of
Sciences, V. 981) Linda Van Speybroeck Gertrudis
Van De Vijver Dani De Waele New York Academy
of Sciences (15. Juni 2006)
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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Literature Field of research make sure its a
recent publication! Unless for historical reasons
I will try to use publication later 2005 2.
Reviews
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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Literature Field of research make sure its a
recent publication! Unless for historical reasons
I will try to use publication later 2005 2.
Reviews
I
Lecture Introduction to DNA methylation and its
impact on gene regulation
12
Literature Field of research make sure its a
recent publication! Unless for historical reasons
I will try to use publication later 2005 2.
Reviews
I
Lecture Introduction to DNA methylation and its
impact on gene regulation
13
Literature Field of research make sure its a
recent publication! Unless for historical reasons
I will try to use publication later 2005 2.
Reviews
Focus on Epigenetics
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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3. Software/Databases to try
http//genome.ucsc.edu/ENCODE/
http//www.epigenome.org/
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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3. Software/Databases to try
http//biq-analyzer.bioinf.mpi-sb.mpg.de/
http//neighborhood.bioinf.mpi-inf.mpg.de/
http//methycancer.genomics.org.cn
http//www.pubmeth.org
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Lecture Introduction to DNA methylation and its
impact on gene regulation
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Seminar Talks

• Databases
• Methylome in Arabidopsis Zilberman
• Methylome in Mammals Schuebeler
• Methylation Prediction - Bhasin/Feltus
• - Zhang group
• - Bock et al.
• HEP
• Biochemistry and Evolutionary aspects
• Deamination/Substitution

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Lecture Introduction to DNA methylation and its
impact on gene regulation