Craniosynostosis

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Craniosynostosis
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Trigonocephaly- Metopic Synostosis
Scaphocephaly - fuse sagittal suture
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Opposing epithelial layers fuse. Epithelial seam
eventually disappears - due to apoptosis -
due to epithelial to mesenchymal transition -
due to migration away from the region
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Ectoderm induces aggregation of ectomesenchyme
initially, then loses ability to induce
aggregation. Ectomesenchyme, after aggregation,
can induce tooth formation in other ectoderm by
inducing the Formation of an enamel knot.
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