Peptide and Protein Structures

1
Peptide and Protein Structures

• A Quest for Understanding Structure and Function

2
Peptide and Protein Structures

• Why are Proteins so Important?
• Proteins are the most diverse group of
  biologically important substances and are often
  considered to be the central compound necessary
  for life.
• Proteins are organic compounds that contain the
  element nitrogen as well as carbon, hydrogen, and
  oxygen.
• Skin and muscles are composed of proteins
  antibodies and enzymes are proteins some
  hormones are proteins and some proteins are
  involved with digestion, respiration,
  reproduction, and even normal vision
• Protein function is directly related to the
  structure of that protein whereas its specific
  shape determines its function.
• If the three-dimensional structure of the protein
  is altered because of a change in the structure
  of the amino acids, the protein becomes denatured
  and does not perform its function as expected.

3
Peptide and Protein Structures

• What makes a molecule an Amino Acid?

Non-Amino Acids are produced within the body
metabolically.
Amino Acid Basic Structure and complete Profile
of Amino Acids http//www.youtube.com/watch?vha
-DNTOooXk
4
Peptide and Protein Structures

• What makes a molecule a Protein?

Proteins are the combining of amino acids
together to form a chain joined by successive
peptide bonding (poly peptides).
http//www.wellesley.edu/Chemistry/chem227/nuclei
cfunction/translation/prtsynth.mov
5
Peptide and Protein Structures

• How are Proteins synthesized?

Protein synthesis is done by combining amino
acids together to form a chain joined by peptide
bonding (poly peptides). http//www.wisc-online.c
om/objects/index_tj.asp?objIDAP1302
6
Peptide and Protein Structures

• Enzymes are highly Functional Proteins

Enzymes functionality are essential to many
metabolic pathways http//www.northland.cc.mn.us/
biology/Biology1111/animations/enzyme.swf
7
Peptide and Protein Structures

• References
• http//www.infoplease.com/cig/biology/proteins.htm
  l
• accessed 7/2/07
• http//www.biology.arizona.edu/biochemistry/proble
  m_sets/aa/aa.html Accessed 7/3/07 accessed 7/3/07
  
• http//www.science.siu.edu/microbiology/micr302/tr
  anslation.htm accessed 7/3/07
• http//www.columbia.edu/cu/biology/courses/c2005/l
  ectures/lec04_06.html 7/4/07
• http//biology200.gsu.edu/houghton/210720'07/lect
  ure27.html
• accessed 7/4/07