VALUTAZIONE DEL RISCHIO CARDIOLOGICO IN CHIRURGIA NON CARDIACA

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Università Vita-Salute di Milano Ospedale San
Raffaele Department of Cardiothoracic and
Vascular Anesthesia Director Prof Alberto
Zangrillo
Landoni G, Marino G, Bignami E, Bove T, Fochi O,
Calabrò MG, Marchetti C, Pappalardo F, Zangrillo
A. Fenoldopam reduces hospital mortality and
the need for renal replacement therapy in
patients undergoing cardiovascular surgery. A
meta-analysis of randomized and (propensity)
matched clinical trials EACTA 2007 Krakow,
Poland, June 15 th 2007

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META-ANALYSIS(cardiac anesthesia)

• 13 randomized studies (9 cardiac surgery 4
  vascular surgery)
• 1059 patients (528 TIVA and 531placebo/best
  available treatment)

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30/5285.7 v 71/53113.3 NNT 13
4
28/5015.5 v 55/50310.9 NNT 19
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MULTICENTRE RCTTOPIC N HOSPITALS N PATIENTS

• VOLATILE ANESTHETICS
• DESMOPRESSIN
• BEST HEMATOCRIT
• FENOLDOPAM
• landoni.giovanni_at_hsr.it

• 3 200
• 6 200
• 9 500
• 27 1000