CLINICAL EVALUATION

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CLINICAL EVALUATION
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Evaluation Overview

• 79 patients monitored over 30 day evaluation
  period
• Pre- and post-weights monitored and adjusted
  using blood volume monitoring
• Provide asymptomatic treatments for all patients
• Blood pressure medications adjusted or
  discontinued

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Patient Weight Changes
51 patients lost weight (avg -2.8 kgs)
18 patients no weight change
10 patients gained weight (avg 1.5 kgs)
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Changes in Profiles
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Significant Changes

• Blood pressure
• 30 patients had blood pressure drops of 20 points
  or more (either systolic or diastolic)
• 49 patients had blood pressure drops of 10 points
  or more (either systolic or diastolic)
• 24 patients are identified as needing their blood
  pressure medications changed or reduced at the
  end of the evaluation
• O2 saturation
• 23 patients were identified as having a drop in
  their O2 saturation
• 15 patients with a drop in O2 also experienced
  morbid events

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Changes in Blood Pressure
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Changes in Blood Pressure

• Average Pre Systolic change -9.6
• Average Pre Diastolic change -7.2
• Average Post Systolic change -12.5
• Average Post Diastolic change -6.7

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Hospitalizations

• Potential for 1027 dialysis treatments during the
  30 day evaluation
• 975 treatments completed 52 dialysis treatment
  days lost to hospitalizations
• 0 treatment days lost due to fluid related events
• 7 treatment days lost due to access related
  events
• 45 treatment days lost due to other related events

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Morbid Events
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Significant Changes

• Morbid events
• 975 dialysis runs completed only
• 122 hypotensive events
• 99 episodes of cramping
• 5 episodes of nausea and vomiting
• 159 administration of normal saline
• 0 episode of dizziness

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Significant Changes

• Crit-Line monitor provides continuous real time
  hematocrit monitoring
• One patient identified with a GI Bleed
• Two patients receiving blood transfusions,
  confirming ending HCT results from transfusion

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Staff Comments

• Physician
• The Crit-Line has made an impact on my patient
  care. Since using the product I havent had any
  admissions for fluid overload events
• Nursing
• I dont seem to have to give any saline for
  volume support like previous treatments.
• The patients seem to have less problems, and it
  makes my day easier.
• I feel more comfortable in taking off 7 or 8 kgs
  with the Crit-Line. I would never have tried for
  so much fluid without the aid of the monitor.
• We had a patient who was in the hospital and
  since coming out and using the Crit-Line, he now
  is almost 30 pounds lighter. Never would I have
  believed it possible, but hes doing great.

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Summary

• Achieve more accurate dry weights
• Clinician can adjust or reduce blood pressure
  medications per new dry weights
• Reduces patient morbid events
• Hematocrit management
• Identify and treat intradialytic hypoxia