Simulation of Light Ion Fragmentation Experiments Using GEANT4

1
Simulation of Light Ion Fragmentation Experiments
Using GEANT4

• Iwan Cornelius, Faiza Bourhaleb,
• Roberto Cirio, Flavio Marchetto

2
Torino INFN

• Italian Heavy Ion Therapy Facility (CNAO)
• Development of beam monitoring hardware
• Treatment planning research
• Physics of ion interaction
• Radiobiology

3
Fragmentation Models

• Current TPS (ANCOD) requires fluence spectra of
  primary and secondaries with depth in patient
  f(Z,E,t)H2O
• Information used with Radiobiological model to
  calculate equivalent dose
• In past produced by GEANT3 w. FREESCO interface
• Investigate models of fragmentation
• Quantum Molecular Dynamics
• JQMD Interface to GEANT4
• GEANT 4.6.0 Includes binary cascade model

4
Model Verification

• Simulate fragmentation experiments
• Schall (GSI) Fragment yields (Zgt4) for varying
  thickness water target
• Matsufuji (NIRS) fragment yields (Zgt1) for
  varying thickness PMMA target
• Gunzert-Marx (GSI) fragment spectroscopy and
  angular dependence (n,p,d,t,He-3,a)

5
G4 Ion Physics

• G4MultipleScattering
• G4ionIonisation
• G4HadronInelasticProcess
• G4TripathiCrossSection
• G4IonsShenCrossSection
• G4BinaryLightIonReaction

6
Schall et.al. 1996

• Beam C-12 676 AMeV
• Target H2O (variable thickness, t)
• Detection system Ionisation Chamber f(DE)
• Information N(Z,t) /No

7
Geometry
8
Results
9
Gunzert-Marx et.al. 2003

• Beam C-12 200 AMeV
• Target H2O (TgtgtR)
• Detection system Detector Telescope f(DE, E),
  TOF system
• Information N(q,E,X)

10
Geometry
11
To do

• Simulate other data from Schall 1996 experiments
  with heavier ions O, N
• Simulate Gunzert-Marx experiment
• Simulate experiment of Matsufuji et.al.
• Quantitative comparison using statistical
  packages?

12
Summary

• Torino section INFN active in treatment planning
  system research for HIT
• Investigating fragmentation model of GEANT4
• Comparison between TPS results using different
  models of ion fragmentation
• Monte Carlo based treatment planning