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THE GLOBAL PLAN TO STOP TB,

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Step 3. Estimating TB control outcomes and impact ... trials; at least 2 vaccines in 'proof of concept' trials; beginning phase III trials ... – PowerPoint PPT presentation

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Title: THE GLOBAL PLAN TO STOP TB,


1
  • THE GLOBAL PLAN TO STOP TB,
  • 2006-2015
  • Giorgio Roscigno
  • Foundation for Innovative New Diagnostics (FIND)
  • on behalf of the Stop TB Partnership
  • Joint Meeting of the DOTS Expansion, TB/HIV and
    DOTS-Plus Working Groups
  • 15 October, 2005
  • Paris

2
Presentation on Global Plan to Stop TB
  • Outline of presentation on the Global Plan
  • what is the Global Plan?
  • why do we need a Global Plan?
  • the process of developing the Plan
  • regional scenarios and Working Group plans
  • expected impact
  • next steps

3
The Global Plan
  • the Stop TB Partnership's plan for TB control
    over the decade 2006-2015, in working towards the
    goal to eliminate TB as a global public health
    problem by 2050
  • a convincing argument for the resources needed
    for action, underpinned by rigorous
    epidemiological analysis with robust budget
    justifications

4
The Global Plan (contd.)
  • What activities are necessary (aimed towards
    reaching the Stop TB Partnership's targets for
    2015)?
  • At what cost?
  • With what impact (implementation WGs)?

5
Why do we need a Global Plan to Stop TB?
  • As a vision of what we can achieveAs a roadmap
    to achieve targetsAs a tool for advocacy and
    fundraisingTo support long-term national
    planningTo stimulate research and development

6
MDG 6 target 8
  • "to have halted by 2015, and begun to reverse the
    incidence" of TB

7
The Stop TB Partnership's targets
  • by 2005
  • at least 70 of people with infectious TB will
    be diagnosed (i.e. under the DOTS strategy) and
    at least 85 cured
  • by 2015
  • the global burden of TB disease (prevalence and
    deaths) will be reduced by 50 relative to 1990
    levels (specifically, this means reducing
    prevalence to 155 per 100,000 and deaths to 14
    per 100,000 per year by 2015)
  • by 2050
  • the global incidence of TB disease will be less
    than 1 case per million population

8
WHO-recommended Stop TB Strategy
  • 1. Pursuing quality DOTS expansion and
    enhancement
  • Political commitment
  • Case detection through bacteriology
  • Standardised treatment, with supervision and
    patient support
  • Effective drug supply system
  • Monitoring system and impact evaluation
  • Additional components
  • 2. Addressing TB/HIV and MDR-TB
  • 3. Contributing to health system strengthening
  • 4. Engaging all care providers
  • 5. Empowering patients and communities
  • 6. Enabling and promoting research

9
Process for developing the Global Plan to Stop TB
  • Process is
  • coordinated by Stop TB Partnership secretariat
  • informed by feedback from first Global Plan
  • guided by the Steering Committee
  • driven by need to achieve 2015 targets in each
    region
  • dependent on contributions of the 7 Stop TB
    Partnership Working Groups (DOTS Expansion
    DOTS-Plus TB/HIV drugs diagnostics vaccines
    and advocacy, communications social
    mobilisation) and of the Secretariat
  • based on developing projections of the expected
    impact and costs of interventions needed to
    achieve 2015 targets (for implementation Working
    Groups)

10
Global Plan has two key dimensions
  • Strategic plans of Working Groups and of
    Secretariat
  • Regional scenarios

11
Benefits for each WG of development of strategic
plan
  • Process
  • engages stakeholders
  • clarifies activities in line with strategic
    direction
  • aids prioritisation
  • identifies resource needs
  • Product
  • sets out activities (with timelines) linked to
    targets
  • enables monitoring of progress towards goal
  • helps resource mobilisation

12
Nine epidemiological regions of the world
AFR high HIV
AFR low HIV
Central Europe
Eastern Europe
Established Market Economy
EMR
LAC
SEAR
WPR
13
Global Plan regional scenarios
  • Regional scenarios
  • Impact and costs of implementation of activities
  • DOTS
  • DOTS-plus
  • TB-HIV

14
Development of regional scenarios
  • Step 1. Defining and costing intervention
    packages
  • Step 2. Estimating the magnitude and pace of
    scaling up of activities
  • Step 3. Estimating TB control outcomes and impact
  • Step 4. Estimating the cost of DOTS expansion,
    DOTS-Plus, TB/HIV and diagnostics

15
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16
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17
Summary of planned achievements of R D WGs
18
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19
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20
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21
Summary of main messages (1)
  • Implementation of the new Stop TB Strategy will
    expand equitable access for all to quality TB
    diagnosis and treatment.
  • Over the ten years of this Plan, about 50 million
    people will be treated for TB under the Global
    Strategy to Stop TB, including about 800,000
    MDR-TB patients, and about 3 million TB/HIV
    patients will be enrolled on ART.
  • Some 14 million lives will be saved from
    2006-2015.
  • The first new TB drug for 40 years will be
    introduced in 2010, with a new short TB regimen
    (1-2 months) shortly after.
  • By 2010 "point of care" diagnostics will enable
    rapid, sensitive and inexpensive detection of
    active TB. By 2012, a diagnostic toolbox will
    accurately identify people with latent TB
    infection and those at high risk of progression
    to disease.

22
Summary of main messages (2)
  • Full funding (US 55 billion) for implementation
    of the Plan would result in achievement of
  • the MDG "to have halted by 2015, and begun to
    reverse the incidence" of TB
  • the Partnerships 2015 targets to halve
    prevalence and death rates from a 1990 baseline
    globally, with enormous progress in all regions
  • the 2015 targets most likely later than 2015 in
  • E Europe and even later in Africa

23
Conclusion together let's Stop TB!
  • Next steps
  • 1. Global Plan launch at the World Economic Forum
    at Davos, 29 January 2006
  • 2. Use the Global Plan
  • a) to mobilise funds
  • to continue current levels of funding
  • to fill the US 35 billion funding gap
  • (depends on the commitment of national
    governments and all those who fund TB control,
    and on fulfilling this commitment)
  • b) to inform the development of regional plans to
    Stop TB
  • c) to assess progress in implementation of the WG
    and secretariat strategic plans
  • 3. Measure impact
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