Determining Brain Pressure NonIntrusively

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Determining Brain Pressure Non-Intrusively

• Avoiding the Spinal Tap
• by
• By Dr. Jacques C. Richard
• JC-Richard_at_CSU.edu
• Dr. Sam Bowen
• S-Bowen_at_CSU.edu

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Cortical Bone Deformation Due to External Pressure

• Apply external pressure to eye
• Measure deformation of thin bone between brain
  and eye cavity with Magnetic Resonance Imaging
  (MRI), Ultrasound, etc.
• Compare deformation seen in MRI to that computed
  from analyzing bone elasticity
• Compute pressure inside brain, whose difference
  from the external pressure led to the deformation

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Skull Views
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Stresses and Deformations of Bone Segments from
Analyses
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Determine Pressure from MRI and Hemodynamics
Computations

• Apply conservation principles to blood flow in
  the brain
• Compute blood flow characteristics and pressure
  and tie-in to MRI data

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View of a Slice of the Brain
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In Progress

• Still need to get high resolution MRI data to get
  the tiny deformations of the thin bone
• Collaborate with research/teaching hospitals that
  have high-resolution MRI equipment
• Collaborate with MRI instrument researchers and
  developers