Redox reactions release energy

1
Redox reactions release energy
Redox reaction (oxidation-reduction)
2
NAD and NADP are electron shuttles
3
Cellular Respiration an overview
Substrate-level phosphorylation
3 metabolic stages glycolysis Krebs
cycle electron transport chain and oxidative
phosphorylation
Oxidative phosphorylation
4
Glycolysis harvests chemical energy by oxidizing
glucose to pyruvate
5
Glycolysis Energy Investment Phase
3) Addition of another phosphate group
1) Glucose is phosphorylated
2) G-6-P is rearranged
5) Conversion b/w the 2 3-carbon sugars
6
6) Two components electron transfer Phosphate
group addition
Glycolysis Energy Payoff Phase
9) Loss of water
7) ATP production
10) ATP production
8) Rearrangement of phosphate group
7
The presence or absence of O2 dictates the fate
of pyruvate
8
The Krebs cycle energy-yielding oxidation
The junction b/w glycolysis and the Krebs cycle
Multienzyme complex 1) Removal of CO2
2) Electron transfer pyruvate
dehydrogenase 3) Addition of CoA
9
The Krebs cycle energy-yielding oxidation
8) electron transfer Malate dehydrogenase
1) Addition of 2 Carbons Citrate synthase
2) Isomerization Aconitase
3) Loss of CO2 electron transfer Isocitrate
dehydrogenase
7) Rearrangement of bonds Fumarase
4) Loss of CO2 electron transfer
a-ketoglutarate dehydrogenase
6) electron transfer Succinate dehydrogenase
5) substrate-level phosphorylation Succinyl
CoA-synthetase
10
Electron transport and ATP synthesis
11
Generation and maintenance of an H gradient
Exergonic flow of e-, pumps H across the
membrane
chemiosmosis
high energy electrons
12
ATP synthase
How does the mitochondrion couple electron
transport and ATP synthesis?