Automation of Protein Crystallography Facilities on the SRS

1
Overview of Protein Crystallography
BIOXHIT Section4
BIOXHIT Sections 2 3
BIOXHIT Section1
5
5
Crystallisation
Phasing
Data Collection
Protein Production
Protein Structure
Target Selection
Structure analysis
Deposition
2
BIOXHIT Section 3
WP3.1 Tracking Crystalline Samples
WP3.2 Crystal Centring
WP3.3 Crystal Characterisation
WP3.5 X-ray Data Collection
WP 3.4 Strategy
Some work packages (e.g. WP3.1, WP 3.2)
reasonably well defined. Others more open ended
3
Overall aim of meeting

• Not to impose BIOXHIT solutions on all
  facilities!
• Encourage common standards e.g.
• Sample tracking
• Communication between modules
• Demonstrate implementations with standards
• People can adopt these or develop their own

4
Pipeline Demonstration

• Demonstrate
• Shipping Crystal to Synchrotron
• X-ray Data Collection
• Return of Results
• Depends on many BIOXHIT deliverables e.g.
• Tracking Samples
• Crystal Centring
• Strategy Determination
• Automation of Data Collection (DNA)
• Remote Operation