From ZINC TABLETS to TECHNOLOGY TRANSFER

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FromZINC TABLETS to TECHNOLOGY TRANSFER

• Nutriset/ Rodael
• France

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A quick history

• WHO project (for studies in Nepal, India and
  Zanzibar)
• Inventory and state of the market (syrups...)
• Possible developments (tablets, capsules,
  syrups)
• Specifications and constraints
• administrable to young children and babies
• quickly dispersible
• acceptable to adults and children
• cheap and easy to transport

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Zinc taste difficult to hide

• Various options to hide the taste of zinc
• - strong concentration of sugar
• - lower concentration of zinc
• - encapsulated tablets

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Other constraints

• Waste management (bottles)
• Stability of the product
• Bioavailability for maximum activity
• Choice of ingredients

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From Development to Production

• Pharmaceutical development nearly 2 years
• Management of critical points, until technique
  completely mastered

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From Production to Technology Transfer
So far

• WHO request for technology transfer
• First contacts with ICDDRB, visits
• Small production in Bangladesh for studies
• Choice of partner.
• Interim period of production in France
• then
• Proper Technology Transfer

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The parties involved

• MOHFW
• WHO
• ICDDRB
• Bill and Melinda Gates Foundation
• USAID
• SMC
• The Futures Group International (Consultants)
• Square Pharmaceuticals
• Other laboratory /ies ?...
• Nutriset Rodael

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a Technology Tranfer should be

• a long term partership and not just selling a
  licence
• a network in the making
• a tool to reach a common goal

should not

• mean a loss of technology
• interfere with the other partys business
  and know-how

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Goals to reach

• Constant improvement of the technology and of the
  product through information sharing
• Globalization and widening of the know-how
• Assurance of equal quality between original
  product and transferred product
• No drifting away from original product (product
  changed or badly copied)

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What is needed

• Understanding of the set-up by all partners
  before the project is launched
• Good knowledge of all partners from the start
• Transparency, visibility and communication
• Adhesion of all parties to the project
• Strong, common will to make the project a success
• Time and a lot of energy
• A solid overall architecture

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Building a technology transfer an architects
job
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Possible difficulties...

• Understanding eachother and eachothers system
  and culture
• Understanding the orgnaization of the project
• Communicating clearly

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Zinc tablets and Technology Transfer Gathering
our strengths and our will
to combat diarrhoea